Nutritional Supplements and Vitamins for Dogs

Milk Can - Soluble powdered milk formula contains proteins, vitamins and trace elements. Indicated for puppies from the first day of life, as well as pregnant females and older animals.

Target species: Dogs, cats

Administration method:

Preparation / administration instructions:
Mix one scoop of powdered milk (10g) with a little warm water.
Add water until the mixture reaches 50 ml.
The temperature of the preparation should be approx. 37⁰C.
Oral administration.
Pregnant adult females: as a secondary meal for 10 days before farrowing, until the day of farrowing.
Puppies: Administer according to the table.
Administer quantitatively until the puppies are satiated.

Ingredients: Dehydrated milk and dairy products, vegetable oils and fats, cereals, minerals, lysine, methionine.

Analytical compounds:
Fats and oils ..........26%
Proteins........................30%
Ash.........................6.5%
Fiber............................0.5%
Calcium.........................1.20%
Phosphorus.........................0.75%
Sodium..........................0.45%
Magnesium...................0.10%
Potassium.......................1.15%
Additives/ kg:

TRACE ELEMENTS
Iron (sulfate)E1...............60 mg
Zinc (sulfate)E6...............60 mg
Manganese (sulfate) E5......50 mg

VITAMINS
Iodine (calcium iodate)E2......1mg
Selenium (Sodium Selenite)E8...0.36mg
Cobalt (carbonate)E3.............0.3mg
A (E672)........................11250IU
D3(E671).......................2000IU
E(a-tocopherol)(3a700).......40IU
C(E300)............................60 mg
B1.................................3.75mg
K3.................................1.25mg

Storage conditions:
Store in a place protected from moisture and direct sun exposure, at temperatures up to 25°C.
Keep the container properly closed

Packaging:
250 g/ 400g with measuring spoon included

Additional information:
ATTENTION! For veterinary use only! Keep out of reach of children! Follow the administration instructions on the label.

Zerokeet Ectoparasite Control for dogs is a long-lasting product. Application is quite simple. Just dilute it in water in a 1:2 ratio and use a cotton swab to apply it all over the dog's body. The most common infestation areas are at the joints, on the neck, behind the ears, and at the tip of the tail. Applying this product helps effectively kill all adult ticks and fleas before they can lay eggs on the pet and continue to multiply.

Features: Kills all fleas and ticks in minutes. Prevents infestation. Easy to use.

For veterinary use only. Shake the bottle before use.

Specifications: Suitable for all dogs. Form - liquid

Composition: Each 10 ml contains (in g): Cedrus deodara 2.0, Pongamia glabara 0.50, Azadirachta indica 0.30, Acorus calamus 0.20, Eucalyptus globulus 0.20, Absorbent bases q.s.

Recommended dosage: Application on the entire body (dilution up to 1:2 in water) at weekly intervals until complete recovery. Zerokeet is applied once a day in cases of lesions, where present.

Other skin conditions - dilution 1:2 to 1:4 in water, depending on the severity of the condition.

Storage instructions: Store in a cool, dry place.

Advocate 250 Dogs (10 - 25 kg), 3 pipettes

Chemical composition:

• Imidacloprid : 100mg/ml
• Moxidectin: 25mg/ml

Pharmaceutical form:

Antiparasitic solution for cutaneous application.

Indications:

for the treatment and prevention of flea infestations (Ctenocephalides spp.).

• reduces the incidence of flea allergy dermatitis.
• larval stages are killed on the animal and in the surrounding environment of treated animals.

for the prevention of heartworm infestations (Dirofilaria immitis)

for the treatment and control of:

• roundworms Toxocara canis, T. leonina (including L1 larval stage and immature adult forms).

• hookworms Ancylostoma caninum, A. braziliense, Uncinaria stenocephala.

• whipworms Trichuris vulpis.

• generalized demodicosis Demodex canis.

• sarcoptic mange Sarcoptes scabiei.

• ear mites Otodectes cynotis.

• lice Trichodectes canis, Linognathus setosus for 6 weeks.

Dosage and administration:

• For dogs between 10 -25 kg, one tube of Advocate 250 is used.
• Administration is done in the dorsal area at the base of the neck for small dogs, and for larger dogs, it can be done in several places along the back.
• The product is applied to the skin, keeping it away from the dog's mouth or eyes.
• The dog's skin must be intact and free of lesions.
• It can be administered to pregnant or lactating bitches.
• The product retains its efficacy after bathing or exposure to rain.
• To reduce re-infestations with new fleas, it is recommended to treat all dogs in a family (household). Other pets in the same family or household should be treated with appropriate products.

Contraindications:

• Not for use in cats.
• Not for use in puppies under 7 weeks of age.

Other information:

• to prevent heartworm infestation, it is advisable to start treatment one month before the mosquito season begins (the host that transmits the larvae) and continue once a month until the mosquito season passes.
• for tapeworms, it is advisable to use internal antiparasitics as ADVOCATE does not act on them but only on roundworms and hookworms.
• for demodicosis, 2 to 4 monthly treatments are required for beneficial effects.
• for mange (ear, sarcoptic), a single treatment is necessary for complete elimination of parasites and signs of disease.

Important: Advocate 250 falls under the pharmacy category. Consult your veterinarian for diagnosis, prescription of medication, or diet according to the specific needs of your dog (cat).

Capsules based on krill oil (oil with high EPA and DHA content with high absorption compared to fish oil)

• activates dermal metabolism
• acts on factors that can cause cardiovascular disease,
• alleviates joint pain,
• improves cognitive functions
• reduces inflammation associated with SICCA keratoconjunctivitis

Composition / capsule:

Krill oil 500 mg,

Phospholipids-Omega 3 fatty acids >70 %,

Omega 3 fatty acids 120 mg,

EPA 57.5 mg,

DHA 32.5 mg,

Astaxanthin 25 mcg

Analytical compounds:

Protein 19.9%, oils and fats 67.5%, fiber 9.2%, ash 2.5%

Dosage: 1 cap / 10 kg / day

Packaging: bottle 60/ 120 tabs

Enteromicro is a probiotic nutritional supplement for dogs and cats, an adjuvant in the imbalance of intestinal flora due to various factors such as: stress, unbalanced diets, medical treatment, deficient immune system. It comes in tablet form, very easy to administer.

Properties: Microencapsulated Lactobacilli (Acidophilus, Faecium, Rhamnosus) pass the gastric barrier intact and reach the small intestine where they have a beneficial effect. Bovine colostrum stimulates the immune response. MOS and FOS restore intestinal microflora. Pectin aids in the formation of compact fecal matter. Maltodextrin has an invigorating action, restoring intestinal homeostasis.

Composition: Brewer's yeast (source of mannan-oligosaccharides (MOS); fructo-oligosaccharides (FOS); maltodextrins; magnesium stearate; colostrum; citrus pectin.

Analytical composition: Crude protein 12.80%; Crude oils and fats 2.25%; Crude ash 2.54%; Crude fiber 4.38%. Vitamins/kg: Vitamin B1 800 mg/kg, Vitamin B2 600 mg/kg, Vitamin B6 800 mg/kg, Vitamin PP 10,000 mg/kg, 2k microorganisms: Lactobacillus Acidophilus (DSM 13241): CFU 375 x 109 Enterococcus Faecium (NCIMB 10415): CFU 375 x 109 Lactobacillus Rhamnosus (DSM 7133): CFU 375 x 109.

PHARMACEUTICAL FORM

Chewable tablets.

Red to reddish-brown marbled, round (tablets for 2-3.5 kg dogs) or rectangular (tablets for >3.5-7.5 kg dogs, >7.5-15 kg dogs, >15-30 kg dogs and >30-60 kg dogs) tablets.

CLINICAL PARTICULARS

Target species: Dogs

Indications for use, specifying the target species

For the treatment of flea and tick infestations in dogs when concurrent prevention of heartworm disease and/or treatment of gastrointestinal nematode infestations is also indicated.

Treatment of flea infestations (Ctenocephalides felis and C. canis) in dogs for 5 weeks. Treatment of tick infestations (Dermacentor reticulatus, Ixodes ricinus, Rhipicephalus sanguineus) in dogs for 4 weeks.

Fleas and ticks must attach to the host and begin feeding to be exposed to the active substance.

Treatment of adult gastrointestinal nematode infestations of the following species: roundworms (Toxocara canis and Toxocara leonina), hookworms (Ancyclostoma caninum and Ancyclostoma braziliense) and whipworms (Trichuris vulpis).

Prevention of heartworm disease (Dirofilaria immitis larval stage) if administered monthly.

Contraindications: Do not use in cases of hypersensitivity to the active substances or to any of the excipients.

Special warnings for each target species

Parasites must begin feeding on the host to be exposed to afoxolaner; therefore, the risk of transmission of infectious diseases cannot be excluded.

Resistance of parasites to a particular class of antiparasitic drugs may develop as a result of frequent use of a compound from that class. Therefore, the use of this product should be based on evaluation of each individual case and local epidemiological information regarding the current susceptibility of the target species to limit the possibility of future selection of resistance.

Maintaining the efficacy of macrocyclic lactones is essential in controlling Dirofilaria immitis. To minimize the risk of resistance selection, it is recommended to test dogs for both circulating antigens and blood microfilariae at the beginning of each preventive treatment period.

Special precautions for use

Special precautions for use in animals

In the absence of available data, treatment of puppies younger than 8 weeks and/or dogs weighing less than 2 kg should only be carried out based on a risk/benefit assessment by the veterinary surgeon.

Dogs living in heartworm endemic areas should be tested for adult heartworm infestation before administering NEXGARD SPECTRA. Infested dogs should be treated with an adulticide at the discretion of the veterinary surgeon to eliminate adult heartworms. NEXGARD SPECTRA is not indicated for the elimination of microfilariae.

The recommended dose must be strictly followed for Collie dogs or other related breeds.

Special precautions to be taken by the person administering the veterinary medicinal product to animals

• This product may cause gastrointestinal upset if ingested.
• Keep tablets in blisters and blister in carton until use.
• In case of accidental ingestion, especially by children, seek medical advice immediately and show the product label.
• Wash hands after use.

Adverse reactions (frequency and seriousness)

In clinical studies, no serious adverse reactions attributable to the afoxolaner-milbemycin oxime combination were observed. Less frequent reactions such as vomiting, diarrhoea, lethargy, anorexia and pruritus were observed. These reactions generally resolved on their own and were short-lived.

The frequency of adverse reactions is defined using the following convention:

- Very common (more than 1 in 10 animals treated show adverse reactions)

- Common (more than 1 but less than 10 animals in 100 animals)

- Uncommon (more than 1 but less than 10 animals in 1,000 animals)

- Rare (more than 1 but less than 10 animals in 10,000 animals)

- Very rare (less than 1 animal in 10,000 animals, including isolated reports).

Use during pregnancy or lactation

Laboratory studies in rats and rabbits have not shown teratogenic effects or any negative effect on the reproductive capacity of males and females. The safety of the veterinary medicinal product has not been established during pregnancy and lactation or for breeding dogs. Use only according to the benefit-risk assessment by the veterinary surgeon.

Interactions with other medicinal products or other forms of interaction

Milbemycin oxime is a substrate of P-glycoprotein (P-gp), and can therefore interact with other P-gp substrates (e.g., digoxin, doxorubicin) or other macrocyclic lactones. Therefore, concomitant treatment with other P-gp substrates may lead to increased toxicity.

Amounts to be administered and administration route

For oral administration.

Dosage:

The product should be administered at a dose of 2.50-5.36 mg/kg afoxolaner and 0.50-1.07 mg/kg milbemycin oxime body weight according to the following table:

For dogs over 60 kg body weight, the necessary combination of chewable tablets should be used.

Method of administration:

The tablets are chewable and palatable for most dogs. If the dog does not accept the tablets directly, they can be administered with food.

Treatment schedule:

The treatment schedule should be based on the veterinary diagnosis and the local epidemiological situation.

NEXGARD SPECTRA can be used as seasonal preventive treatment against fleas and ticks (replacing treatment with a monovalent product acting only against fleas and ticks) in dogs concurrently infested with gastrointestinal nematodes. A single treatment is effective against gastrointestinal nematodes. After treating nematode infestations, treatment against flea and tick infestations can be continued by applying the monovalent product.

Disease: Heartworm disease:

NEXGARD SPECTRA kills Dirofilaria immitis larvae for one month after their transmission by mosquitoes, so the product should be administered at regular monthly intervals throughout the vector season, starting one month after the first exposure to mosquitoes. Treatment should be continued until one month after the last exposure to mosquitoes. To establish a treatment routine, it is recommended to administer the treatment on the same day of the month.

If replacing another heartworm prevention product, the first treatment with NEXGARD SPECTRA should begin on the day the previous medication was due.

Dogs living in or travelling to a heartworm endemic region may be infested with adult heartworms. No therapeutic effect against adult Dirofilaria immitis has been established. Therefore, it is recommended that all dogs 8 months of age or older, living in heartworm endemic areas, be tested for adult heartworm infestation before being treated with a heartworm prevention product.

Overdose (symptoms, emergency procedures, antidotes), if applicable

No adverse reactions were observed in healthy puppies over 8 weeks of age after 6 treatments with 5 times the maximum dose.

PHARMACOLOGICAL PROPERTIES

Pharmacotherapeutic group: antiparasitic products, endectocides, milbemycin combinations.

ATC veterinary code: QP54AB51

Pharmacodynamic properties

Afoxolaner:

Afoxolaner is an insecticide and acaricide belonging to the isoxazoline family.

Afoxolaner acts by interacting with chloride ion channels, primarily those with a binding site for the neurotransmitter gamma-aminobutyric acid (GABA), thereby blocking pre- and post-synaptic transfers of chloride ions across the cell membrane. This results in uncontrolled activity of the central nervous system and the death of insects and mites. The selective toxicity of afoxolaner between insects/mites and mammals is a consequence of the characteristic sensitivity of insect/mite GABA receptors versus those of mammals.

Afoxolaner is active against adult fleas and some tick species such as Rhipicephalus sanguineus, Dermacentor reticulatus and D. variabilis, Ixodes ricinus and I. scapularis, Amblyomma americanum and Haemaphysalis longicornis.

The product kills fleas before egg laying and thus prevents contamination of the home. It can be used as part of a treatment strategy for the control of flea allergy dermatitis (FAD).

Milbemycin oxime:

Milbemycin oxime is an antiparasitic endectocide belonging to the macrocyclic lactone group. Milbemycin oxime is a mixture of milbemycin A4 and milbemycin A3 (in a 20:80 ratio for A3:A4). It is isolated from the fermentation of Streptomyces milbemycinicus.

Milbemycin oxime acts by disrupting glutamate-activated neurotransmission in invertebrates. Milbemycin oxime increases the membrane permeability of nematodes and insects to chloride ions through glutamate-controlled chloride ion channels (linked to GABA and glycine receptors in vertebrates).

This leads to neuromuscular membrane hyperpolarisation and paralysis and death of parasites.

Pharmacokinetic particulars

Afoxolaner is absorbed very quickly systemically. The absolute bioavailability obtained was 88%. The mean maximum plasma concentration (Cmax) was 1822 ± 165 ng/ml, 2-4 hours (Tmax) after a dose of 2.5 mg/kg afoxolaner.

The volume of distribution of Afoxolaner in tissues is 2.6 ± 0.6 l/kg and the clearance value is 5.0 ± 1.2 ml/h/kg. The half-life is approximately 2 weeks in dogs.

Plasma concentrations of Milbemycin oxime increase rapidly within the first 1-2 hours (Tmax) indicating rapid absorption from the tablet. The absolute bioavailability obtained was 81% for factor A3 and 65% for A4 respectively. The mean maximum plasma concentration (Cmax) after oral administration was 1.6 ± 0.4 days and 42 ± 11 ng/ml for A3, 3.3 ± 1.4 days and 246 ± 71 ng/ml for A4.

The volume of distribution of Milbemycin oxime in tissues is 2.7 ± 0.4 and 2.6 ± 0.6 l/kg for form A3 and A4 respectively. Both forms have a low clearance value of 75 ± 22 ml/h/kg for A3 and 41 ± 12 ml/h/kg for A4.

PHARMACEUTICAL PARTICULARS

List of excipients

• Maize starch
• Soya proteins
• Braised beef flavour
• Povidone (E1201)
• Macrogol 400
• Macrogol 4000
• Macrogol 15 hydroxystearate
• Glycerol (E422)
• Medium chain triglycerides
• Citric acid monohydrate (E330)
• Butylhydroxytoluene (E321)

Incompatibilities: Not applicable.

Shelf life: Shelf life of the veterinary medicinal product as packaged for sale: 2 years

Special precautions for storage: Keep the blister in the secondary packaging to protect from light.

Nature and composition of primary packaging

This veterinary medicinal product is individually packed in thermoformed PVC blisters sealed on the back with aluminium foil (Aclar/PVC/Alu).

1 cardboard box containing one blister with 1, 3 and 6 chewable tablets.

Not all pack sizes may be marketed.

Special precautions for the disposal of unused veterinary medicinal products or waste materials derived from the use of such products

Any unused veterinary medicinal product or waste materials derived from the use of such products should be disposed of in accordance with local requirements.

Dialix Vesical & Prostate helps to:

• maintain bladder muscles and sphincter tone
• healthy bladder function/emptying
• for males: optimal prostate function.

For spayed females and older animals.

Ingredients: Cucurbita pepo 150 mg, Dioscorea villosa 150 mg, Rehmannia glutinosa 150 mg, Glycine max 100 mg, Zea mays 60 mg, Serenoa repens 60 mg, Olea europea 50mg, Vitamin B6 25 mg.

Directions for use:

1 tablet/ 10 kg body weight/ daily

Concentrated liquid formula based on bioavailable Omega 3 Fatty Acids 283.2 mg, of which EPA (51mg) and DHA (190.8 mg) and Vit A (1,737 IU), D3 (34 IU).

To support cardiac, locomotor functions and sports performance.

For pregnant females to support fetal brain development.

Advantix is an external antiparasitic product containing imidacloprid and permethrin, and is highly effective in treating flea and tick infestations for one month after a single application.

Composition
Each dose (pipette) contains:

Excipients: Butylated hydroxytoluene 1.0 mg/ml (E321, as antioxidant):

Indications
For the treatment and prevention of flea infestation (Ctenocephalides canis, Ctenocephalides felis).
Fleas on dogs are killed within one day of treatment. One treatment prevents future flea infestations for four weeks. The product
can be used as part of a treatment strategy against flea allergy dermatitis (FAD).
The product has acaricidal and repellent activity for up to four weeks (Rhipicephalus sanguineus, Ixodes
ricinus) or three weeks (Dermacentor reticulatus) against tick infestations.
Ticks already present on the dog may not be killed within two days after treatment and may remain attached and visible. Therefore, it is
recommended to remove ticks present on the dog at the time of treatment to prevent them from attaching and feeding.
One treatment provides repellent (anti-feeding) action against sand flies for two weeks (Phlebotomus papatasi) or three
weeks (Phlebotomus perniciosus) against mosquitoes for two (Aedes aegypti) and four (Culex pipiens) weeks and against stable flies
(Stomoxys calcitrans) for four weeks.
Sandflies Phlebotomus perniciosus 3 weeks
Phlebotomus papatasi 2 weeks
Mosquitoes Aedes aegypti 2 weeks
Culex pipiens 4 weeks
Stable flies Stomoxys calcitrans 4 weeks

Contraindications
In the absence of available data, the product should not be used in puppies younger than 7 weeks.
Do not use in cases of known hypersensitivity to the active substances.
Do not use in cats.

Adverse reactions
Transient skin sensitivity (with increased pruritus, alopecia, and erythema at the application site) or apathy may rarely occur.
Poisoning of dogs after accidental ingestion may occur in rare cases. In these cases, neurological signs such as
tremors and apathy may also occur. Symptomatic treatment should be applied under the supervision of a veterinarian. There is no specific antidote.
If you notice any serious reactions or other effects not mentioned in this leaflet, please inform your veterinarian.

Target species
Dogs.

Dosage for each species, route(s) of administration and method of administration
Dosing regimen:
The minimum recommended dose is: 10 mg/kg body weight (b.w.) imidacloprid and 50 mg/kg body weight (b.w.) permethrin, equivalent to
0.1ml/kg b.w. Advantix spot-on solution for dogs.

Dog weight (kg) Pipette size to be used Volume (ml) Imidacloprid (mg/kg b.w.) Permethrin (mg/kg b.w.)

>25 kg - 40 kg Advantix spot-on solution for dogs over 25 kg 4.0 ml 10 - 16 50 - 80
> 40 kg use the appropriate combination of pipettes

To reduce re-infestation with new fleas, it is recommended that all dogs in a household be treated. Other pets in
the same family or household should be treated with appropriate products. For fleas originating from the animal's environment,
the additional use of an appropriate product for the treatment against adult fleas and their developmental stages is recommended. The product is active even if the animal is wet. However, prolonged exposure to water should be avoided. In case of prolonged exposure
to water, the efficacy of the product decreases. Even in this case, it should not be treated more frequently than once a week. If
the animal needs to be shampooed, it is advisable to apply Advantix spot-on solution for dogs after two weeks
to ensure the product's efficacy.

Method of administration.
Remove one pipette from the package. Hold the pipette upright, twist the cap and remove it. Turn the cap upside down and use it
to seal the pipette (by twisting and pressing on the seal, as shown in the picture).
For dogs weighing 10 kg or less:
With the dog standing, part the hair between the shoulder blades until the skin is visible. Apply the tip of the pipette directly to the skin and
by squeezing firmly several times, empty the contents of the pipette. Apply only to unbroken skin.
For dogs weighing more than 10 kg:
With the dog standing, the entire contents of the Advantix spot-on solution for dogs pipette will be applied evenly in four spots,
starting between the shoulder blades and extending to the base of the tail. At each spot, part the hair until the skin is visible. Apply the tip of the pipette to the skin and
gently squeeze to release some of the solution onto the skin.

Recommendations for correct administration
For external use only.
Apply only to unbroken skin.
Do not apply a large amount of solution in one spot, as it may run down the sides of the dog.

Withdrawal period
Not applicable.

Special precautions for storage
Keep out of the sight and reach of children.
Do not freeze.
After opening the aluminum pouch, store in a dry place and do not store above 30°C.
The abbreviation used for the expiry date on the label, pipette, and pouch is EXP.

Special precautions for use in animals
The content of the pipette must not come into contact with the eyes and mouth of the treated dog.
Pay attention to the correct administration of the product as described in the "Method of administration" section. In particular, oral ingestion
by licking the application site or contact with other animals should be avoided.
Do not use on cats.
This product is highly toxic to cats and can cause death due to the physiological peculiarities of cats
who are unable to metabolize certain compounds, including permethrin. To prevent accidental exposure of
cats to this product, treated dogs should be kept separate from cats after treatment until the application site is dry.
Measures should be taken to prevent cats from licking the application site of dogs that have been treated with this product. Seek
immediate veterinary assistance if this occurs.
Consult your veterinarian before using this product in sick and debilitated animals.
Since the product is hazardous to aquatic organisms, treated dogs must under no circumstances be allowed to enter any surface waters
for at least 48 hours after treatment.

Special precautions to be taken by the person administering the veterinary medicinal product to animals
Avoid contact with skin, eyes, or mouth. Do not eat, drink, or smoke during product application.
Wash hands thoroughly after product application.
If the product accidentally comes into contact with skin, wash the area immediately with soap and water.
Individuals with known skin sensitivity may be particularly sensitive to this product.
If the product accidentally gets into the eyes, wash the eyes with plenty of water. If skin or eye symptoms persist, or the product is
accidentally swallowed, seek immediate medical advice and show the doctor the product leaflet.
Treated dogs should not be allowed to play, especially with children, until the application site is dry. To be safe, treat dogs, for
example, in the evening. In this case, treated dogs are not allowed to sleep with their owners, especially if they are children.

Special precautions for the disposal of unused product or waste materials, if applicable
After use, place the cap back on the pipette. Any unused veterinary medicinal product or waste materials derived from such products
should be disposed of in accordance with local requirements.

Other information
Advantix spot-on solution for dogs is a topical ectoparasiticide containing imidacloprid and permethrin.
This combination acts as an insecticide, acaricide, and repellent.

Imidacloprid is an ectoparasiticide belonging to the chloronicotinyl compound group. Chemically, it can be classified
as chloronicotinyl nitroguanidine. Imidacloprid is effective against adult fleas and their larval stages. In addition to
its efficacy against adult fleas, the larvicidal efficacy of the substance has also been demonstrated for areas in the animal's habitat.
The product provides repellent (anti-feeding) action against ticks, sand flies, and mosquitoes, thereby preventing
parasite blood feeding and reducing the risk of transmission of vector-borne diseases (Canine Vector-Borne Disease or
CVBD, such as borreliosis, rickettsiosis, ehrlichiosis, leishmaniasis).
It can be used during pregnancy and lactation.
The solvent in Advantix spot-on solution for dogs may stain certain materials such as leather, fabrics, plastic, and finished surfaces. Allow
the application site to dry before contact with such materials.

Packaging:
Pipettes of 0.4 ml, 1.0 ml, 2.5 ml, 4.0 ml
Blister containing 1, 2, 3, 4, or 6 individual pipettes.
Not all pack sizes may be marketed.
For any information about this veterinary medicinal product, please contact the local representative of the marketing authorization holder.

Marketing Authorization Holder
Bayer Animal Health GmbH, D-51368 Leverkusen, Germany

Apply directly into the oral cavity - Ideal for use on the go or between brushings.

Instantly eliminates bad breath
Reduces dental stains and discolorations
Supports gum health
Destroys tartar and plaque

Dedicated to dogs & cats

Indicated for combating coprophagia in dogs and cats.
Specially selected composition, with scientifically proven action.
Beneficial effects on the digestive system.

Coprophagia is common in the animal world and manifests as the ingestion of feces. The animal may eat its own feces or feces from other animals. It is a dangerous pathology for both the health of the animal and the health of the family in which it lives.
It is based on physiological factors (gastrointestinal disorders, malabsorption, malnutrition, poor diet, etc.) or behavioral factors (stress, lack of stimuli, desire for attention, etc.).

Indications:
Coprovet is a complementary support formula, dedicated to dogs and cats suffering from imbalances in the gastrointestinal microflora. It can be administered as an adjuvant to animals affected by coprophagia due to malabsorption or poor digestion.

Composition:
13.1.6 dehydrated pineapple, 4.1.14 fructooligosaccharides (FOS), 7.12.1 Yucca schidigera, 13.3.1 corn starch, 11.2.10 magnesium stearate.

Additives (g / kg): 4b Enterococcus faecium, 1k Lactobacillus rhamnosus, 1E551b colloidal silicon 9 g.

Technological additives: 1E460 microcrystalline cellulose 186 g.

Description:
Dried pineapple extract - source of beneficial ingredients (micro and macro-elements), including bromelain, which contains several substances: proteolytic enzymes responsible for protein digestion, peroxidase, phosphatase, protease inhibitors, calcium.
Bromelain prevents malabsorption due to the action of the following substances in its composition: protein-degrading substances, digestion-stimulating substances, substances that ensure optimal small intestine function, anti-inflammatory substances.
Fructooligosaccharides (FOS), mainly from artichoke, are used by beneficial intestinal microflora for optimal multiplication and development.
Lactobacillus rhamnosus supports the development of beneficial bacteria at the expense of harmful ones.
Enterococcus faecium - a specific probiotic which, in addition to stimulating local immunity, supports the general immunity of the body.
Yucca Schidigera eliminates the unpleasant smell of feces and unpleasant odors from the animal. Beneficial intestinal effects against inflammatory conditions in the colon.

Dosage and administration:
Dogs and cats up to 10 kg body weight - 1 capsule/ day.
Dogs over 10 kg body weight - 2 capsules/ day.
Capsules can be administered as such or with food. Always ensure the animal has fresh water for drinking.

Analytical compounds:
Crude protein - 1.6%, crude ash - 1.85%, crude fat - 1.2%, crude fiber - 14.3%, moisture - 5.7%.

Packaging: 30 caps
Warning: keep out of reach of children. For veterinary use only. Observe the recommended dosage. The product is administered on the recommendation of a veterinarian.

Advocate 100 for Dogs (4 - 10 kg), 3 pipettes

Chemical composition:

• Imidacloprid: 100mg/ml
• Moxidectin: 25mg/ml

Pharmaceutical form:

• Antiparasitic solution for cutaneous application.

Indications:

for the treatment and prevention of flea infestations (Ctenocephalides spp.).

• reduces the incidence of flea allergy dermatitis.
• larval stages are killed on the animal and in the surrounding environment of treated animals.

for the prevention of heartworm infestations (Dirofilaria immitis)

for the treatment and control of:

• roundworms Toxocara canis, T. leonina (including L1 larval stage and immature adult forms).

• hookworms Ancylostoma caninum, A. braziliense, Uncinaria stenocephala.

• whipworms Trichuris vulpis.

• generalized demodicosis Demodex canis.

• sarcoptic mange Sarcoptes scabiei.

• ear mites Otodectes cynotis.

• lice Trichodectes canis. Linognathus setosus for 6 weeks.

Dosage and administration:

• For dogs weighing between 4 - 10 kg, one tube of Advocate 100 is used;
• Administration is done in the dorsal area at the base of the neck for small dogs, and for large dogs, it can be applied in several places along the back.
• The product is applied to the skin, keeping it away from contact with the dog's mouth or eyes.
• The dog's skin must be intact and without lesions.
• It can be administered to pregnant or lactating bitches.
• The product retains its efficacy after bathing or exposure to rain.
• To reduce re-infestation with new fleas, it is recommended that all dogs in a household be treated. Other pets in the same family or household should be treated with appropriate products.

Contraindications:

• Do not use on cats.
• Do not use on puppies younger than 7 weeks.

Other information:

• for the prevention of heartworm infestation, treatment should begin one month before the mosquito season (the host that transmits the larvae) and continue once a month until the mosquito season passes.
• for intestinal tapeworms (teniae), it is recommended to use internal antiparasitics because ADVOCATE does not act on them, only on roundworms and hookworms.
• for demodicosis, 2 to 4 monthly treatments are necessary to achieve beneficial effects.
• for mange (ear, sarcoptic), a single treatment is necessary for complete elimination of parasites and disease signs.

Important: Advocate 100 falls under the pharmacy category. Consult your veterinarian for diagnosis, prescription of medication, or diet according to your dog's (cat's) specific needs.

Clorexyderm Solution 4% is an antiseptic solution with chlorhexidine digluconate for dogs and cats.

Clorexyderm Solution is an antiseptic, rehydrating, emollient solution recommended for maintaining skin health and supplementing the general treatment of superficial and deep pyoderma of bacterial and mycotic etiology (G+ and G- germs, pathogenic fungi and yeasts, Malassezia, Pachydermatis, Microsporus canis, Tricophyton mentagrophites...).

Composition: 4% chlorhexidine digluconate and excipients: polyethylene glycol, glycerin, deionized water.

Dosage and administration:

Apply by spraying onto affected areas. Frequency of administration: once a day between shampoos. For highly reactive animals, it is recommended to apply the product with a clean cotton pad. Treated areas should be allowed to dry naturally.

Warnings:

The use of this product does not exclude general treatment.

Consult a veterinarian.

Precautions:

Avoid contact with eyes.

If necessary, rinse eyes thoroughly with water and seek medical advice.

Keep out of reach of children.

In case of accidental ingestion, seek medical advice immediately and show the product label.

Do not use this product with other disinfectants.

Avoid contact of the product with food or food and drink containers.

Consult a veterinarian before use in pregnant or lactating animals, puppies, or convalescing animals.

Keep the bottle tightly closed at room temperature.

Product for external use only.

MSM, 60 tablets is a rich source of bioavailable sulfur. Sulfur is an essential mineral in all animal diets. In the past, they consumed it in fresh and unprocessed foods.

Indications:

Skin: Contributes to anti-allergic treatments and dermatitis (eliminates residual irritation in dogs undergoing allergic treatments), strengthens nails and fleshy parts, prevents alopecia, promotes healthy and shiny skin, improves skin effects after distemper.

Locomotor system: muscle pain, long-term arthritis, rheumatism, bursitis

Metabolic function: acute gastritis, diuretic effect, respiratory allergies

Presentation: Bottle with 60 tablets

Diamel Pets Supplement for Dogs and Cats, which regulates blood pressure and stimulates the pancreatic metabolism of pets.

Diamel Pets contains a unique blend of amino acids, vitamins and trace elements that help normalize glucose, cholesterol and uric acid levels.

In addition, the supplement contains antioxidants for cell protection, and helps normalize blood sugar.

Three vitamins, folic acid (vitamin B9), cyanocobalamin (B12) and pyridoxine (vit B6) stop the formation of homocysteine and help reduce cholesterol levels.

The supplement contributes to protection against cardiovascular and degenerative diseases, such as diabetic retinopathy.

Ingredients: cranberry 0.015 g, maltodextrin 0.15 g.

Nutritional additives: ascorbic acid 0.3 g, pyridoxal 0.00495 g, folic acid 0.495 mg, cyanocobalamin 0.0024 mg, zinc sulfate (E6) 0.09 g, calcium pantothenate 0.015 g, arginine 0.5325 g, glycine 0.1065 g, fumaric acid 0.5325 g, L-carnitine 0.5325g, ornithine 0.2655 g, L-cysteine 0.213 g, liver flavor 0.6 g, potassium sorbate 0.3 g, sodium benzoate 0.3 g water q.s.ad 150 ml.

Analytical constituents: proteins 3.17g, carbohydrates 0.7 g, fats 0.38 g. Energy 19Kcal (79.55 Kj).

Recommended dosage: Dogs and cats: 1ml per 5 kg body weight every 12 hours.

Other species: 1ml every 12 hours. Consult your veterinarian before administration.

GeriatiVet Dog Large Breed 820mg is recommended for treating elderly dogs who, due to aging, need an increased intake of substances that can protect them from various age-related disorders.

Glucosamine is the most researched and recognized nutrient that helps reduce joint risks in elderly dogs suffering from osteoarthritis.

β-1,3/1,6 Glucan isolated from the cell wall of Saccharomyces Cerevisiae is a polysaccharide whose characteristic components activate the immune system.

L-Carnitine plays an important role in the metabolism of long-chain fatty acids and in energy production.

Lutein contributes to increasing a dog's immunity by activating cellular and humoral immune responses.

HMB is a natural derivative of leucine, as is beta-hydroxy-beta-methylbutyrate. It protects the cellular skeleton of muscles against degradation and helps maintain muscle mass, especially in elderly dogs who are prone to skeletal muscle atrophy.

Omega 3 fatty acids are among the most important components of neuronal membranes.

Alpha-lipoic acid is one of the most powerful antioxidants and protects neurons against harmful effects caused by free radical reactions or conditions arising from excessive cellular membrane oxidation.

Recommended dosage:

GeriatiVet Large Breeds 820 mg
For dogs weighing 15-30 kg BW - 1 tablet/day
For dogs weighing over 30 kg BW - 2 tablets/day

Composition:
Meat and animal by-products, rice flour, potato starch, dextrose, ginger 4.8%, chamomile, Icelandic moss, eggs and egg products, liquorice, fennel, lemon balm

Analytical constituents:

• Crude protein 24.7%
• Crude fiber 5.3%
• Crude oils u. -Fats 5.3%
• Crude ash 7.1%

Nausi Tab® does not contain allergenic ingredients from soy, gluten-containing grains, milk, beef or pork.

Administration

Chewable tablet for single administration or feeding with a small meal. Half an hour to an hour before car journeys or stressful situations, if necessary.

• up to 10 kg ½ chewable tablet
• from 10 to 20 kg 1 chewable tablet
• over 20 kg 2 chewable tablets

The dose can be repeated after 3 to 4 hours.

In case of morning sickness or sensitive stomach, Nausi Tab® can be administered morning and evening.

Fresh water must be provided permanently during the administration of Nausi Tab®.

.

Indications:
Growing puppies (especially large breeds)
Senior dogs and cats
Dogs involved in sports or working dogs
Nutritional support for animals with joint conditions: osteoarthritis, dysplasia, trauma, or orthopedic surgeries.

Ingredients/tablet:
Glucosamine 350mg, MSM 350mg, Hemp 300mg, Chondroitin sulfate 300mg, Hydrolyzed Collagen II 225mg, Dried Acerola extract 100mg, Krill 75mg, Excipients.

Dosage:
1 tablet (2g) per 20 kg body weight/day.
Administer with food: phytocannabinoids are fat-soluble. Krill provides oil (fatty acids) which helps in the absorption of phytocannabinoids.
If administered with food, fats from the food will also contribute to better absorption of active substances from hemp.

Under 5kg - ¼ tab/day
5-10kg - ½ tab/day
10-20kg - 1 tab/day

Hemp (Cannabis sativa): source of phytocannabinoids (mostly CBD). Regulates inflammatory processes
Pain management (at neurological level) → improves quality of life
Krill: source of OMEGA-3 fatty acids in phospholipid form → more efficient compared to those extracted from plants or fish. Regulates inflammatory processes at joint and muscle level. Improves mobility
MSM: highly bioavailable sulfur.
Collagen, Glucosamine, Chondroitin: synthesis materials for cartilage regeneration.
Acerola fruits: plant rich in vitamin C, an essential enzymatic cofactor for the 3D structure of collagen.
COLLAGEN, GLUCOSAMINE, CHONDROITIN & ACEROLA (VIT. C)
Nourish and protect cartilage, ligaments, and tendons
Provide synthesis material
Protect against oxidative processes

Packaging: 30 TABS/ 90 TABS

Storage: Store in a dry place, away from direct sunlight.
CAUTION: For veterinary use only! Keep out of reach of children! Consult your veterinarian before administration or changing dosage!
Lot / Expiry: check packaging

Combined action: diuretic, antilithic, and urinary acidifier.

Complete formula with 9 active ingredients that work synergistically.

For short-term management of FLUTD, promotes struvite dissolution, prevents their recurrence, support in case of mild urinary infections.

Ingredients:
Vaccinium macrocarpon 100mg, Taraxacum officinale 50 mg, vitamin C 60 mg. Arctostaphylos uva-ursi 200 mg, Phyllantus niruri 150 mg, Althaea officinalis 100 mg, L-Methionine 100 mg, Zea mays 60 mg, Olea europea 50 mg.

Administration method:

1 tab/ 10 kg BW/ daily

Dietary supplement for supporting renal functions in cases of chronic kidney disease in dogs and cats.

Dialix Lespedeza PLUS 15 contains:

Lespedeza 300mg - increases diuresis and reduces uremia

CaCO3 450mg - reduces enteric phosphorus absorption.

Contains flavonoids that produce renal vasodilation and stimulate renal parenchyma.

Suitable for long-term use.

Directions for use:

1 tab/ 5 kg BW/ every 12 h

Dietary supplement for supporting renal function in chronic kidney disease in dogs and cats.

Lespedeza capitata (100 mg in DL 5) - increases diuresis and reduces uremia.

Contains flavonoids that cause renal vasodilation and stimulate the renal parenchyma.

Very safe: subacute toxicity tests (5x 30 days) and chronic toxicity tests (5x 90 days) did not produce changes in weight, nor clinical, hematological or histopathological changes.

Ideal for prolonged management of kidney conditions.

Suitable for long-term use.

Administration:

1 tablet/ 1 kg BW/ every 12 h