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Advantix is an external antiparasitic product containing imidacloprid and permethrin, and is very effective in treating flea and tick infestations for one month after a single application.
Composition
Each dose (pipette) contains:
| Pipette | Imidacloprid | Permethrin | E321 | |
| Advantix spot-on solution for dogs up to 4 kg | 0.4 ml | 40 mg | 200 mg | 0.4 mg |
| Advantix spot-on solution for dogs from 4 kg to 10 kg | 1.0 ml | 100 mg | 500 mg | 1.0 mg |
| Advantix spot-on solution for dogs from 10 kg to 25 kg | 2.5 ml | 250 mg | 1250 mg | 2.5 mg |
| Advantix spot-on solution for dogs over 25 kg | 4.0 ml | 400 mg | 2000 mg | 4.0 mg |
Excipients: Butylhydroxytoluene 1.0 mg/ml (E321, as an antioxidant):
Indications
For the treatment and prevention of flea infestation (Ctenocephalides canis, Ctenocephalides felis).
Fleas on dogs are killed within one day of treatment. One treatment prevents future flea infestations for four weeks. The product
can be used as part of a treatment strategy against flea allergy dermatitis (FAD).
The product has acaricidal and repellent activity for up to four weeks (Rhipicephalus sanguineus, Ixodes
ricinus) or three weeks (Dermacentor reticulatus) against tick infestations.
Ticks already present on the dog may not be killed within two days of treatment and may remain attached and visible. Therefore,
it is recommended to remove ticks present on the dog at the time of treatment to prevent them from attaching and feeding.
One treatment provides repellent (anti-feeding) action against sandflies for two weeks (Phlebotomus papatasi) or three
weeks (Phlebotomus perniciosus), against mosquitoes for two (Aedes aegypti) and four (Culex pipiens) weeks, and against stable flies
(Stomoxys calcitrans) for four weeks.
Sandflies Phlebotomus perniciosus 3 weeks
Phlebotomus papatasi 2 weeks
Mosquitoes Aedes aegypti 2 weeks
Culex pipiens 4 weeks
Stable flies Stomoxys calcitrans 4 weeks
Contraindications
In the absence of available data, the product should not be used in puppies younger than 7 weeks.
Do not use in known cases of hypersensitivity to the active substances.
Do not use in cats.
Adverse reactions
Transient dermal sensitivity (with increased pruritus, alopecia and erythema at the application site) or apathy may rarely occur.
Poisoning of dogs after accidental ingestion may occur in rare cases. In these cases, neurological signs such
as tremors and apathy may also appear. Symptomatic treatment should be applied under the supervision of a veterinarian. There is no specific antidote.
If you notice serious reactions or other effects not mentioned in this leaflet, please inform your veterinarian.
Target species
Dogs.
Dosage for each species, route(s) of administration and method of administration
Dosing regimen:
The minimum recommended dose is: 10 mg / kg body weight (b.w.) imidacloprid and 50 mg / kg body weight (b.w.) permethrin equivalent to
0.1ml/kg b.w. Advantix spot-on solution for dogs.
Dog weight (kg) Pipette size to be used Volume (ml) Imidacloprid (mg/kg b.w.) Permethrin (mg/kg b.w.)
>25 kg - 40 kg Advantix spot-on solution for dogs over 25 kg 4.0 ml 10 - 16 50 - 80
> 40 kg use the appropriate combination of pipettes
| Dog weight (kg) | Pipette size to be used | Volume (ml) | Imidacloprid (mg/kg b.w.) | Permethrin (mg/kg b.w.) |
| <=4 kg | Advantix spot-on solution for dogs up to 4 kg | 0.4 ml | minimum 10 | minimum 50 |
| >4 kg - 10 kg | Advantix spot-on solution for dogs from 4 kg to 10 kg | 1.0 ml | 10 - 25 | 50 - 125 |
| >10 kg - 25 kg | Advantix spot-on solution for dogs from 10 kg to 25 kg | 2.5 ml | 10 - 25 | 50 - 125 |
| >25 kg - 40 kg | Advantix spot-on solution for dogs over 25 kg | 4.0 ml | 10 - 16 | 50 - 80 |
| > 40 kg | use the appropriate combination of pipettes |
To reduce re-infestations with new fleas, it is recommended that all dogs in a family (household) be treated. Other pets in
the same family or household should be treated with appropriate products. For fleas originating from the animal's environment,
the additional use of an appropriate product for the treatment against adult fleas and their developmental stages is recommended. The product is effective even if the animal is wet. However, prolonged exposure to water should be avoided. In case of prolonged exposure
to water, the efficacy of the product decreases. Even in this case, treatment should not be more frequent than once a week. If
the animal needs to be shampooed, it is advisable to apply Advantix spot-on solution for dogs two weeks later
to ensure the product's efficacy.
Method of administration.
Remove one pipette from the package. Hold the pipette upright, twist the cap and remove it. Turn the cap upside down and use it to
unseal the pipette (by twisting and pressing on the seal, as shown in the photo).
For dogs weighing 10 kg or less:
With the dog standing, part the hair between the shoulder blades until the skin is visible. Apply the tip of the pipette directly to the skin and
by squeezing firmly several times, empty the contents of the pipette. Apply only to unbroken skin.
For dogs weighing more than 10 kg:
With the dog standing, the entire contents of the Advantix spot-on solution for dogs pipette will be applied evenly in four spots
starting between the shoulder blades and extending to the base of the tail. At each spot, part the hair until the skin is visible. Apply the tip of the pipette to the skin and
gently squeeze to release some of the solution onto the skin.
Recommendations for correct administration
For external use only.
Apply only to unbroken skin.
Do not apply a large amount of solution in one spot as this may run off the sides of the dog.
Withdrawal period
Not applicable.
Special precautions for storage
Keep out of the reach and sight of children.
Do not freeze.
After opening the aluminum pouch, store in a dry place and do not store at a temperature higher than 30°C.
The abbreviation used for the expiry date on the label, pipette and pouch is EXP.
Special precautions for use in animals
The contents of the pipette must not come into contact with the eyes and mouth of the treated dog.
Pay attention to the correct administration of the product as described in the "Method of administration" section. In particular, oral ingestion
by licking the application site or contact with other animals should be avoided.
Do not use in cats.
This product is highly toxic to cats and can cause death due to the physiological peculiarities of cats,
who are unable to metabolize certain compounds, including permethrin. To prevent accidental exposure of
cats to this product, treated dogs should be kept separate from cats after treatment until the application site is dry.
Measures should be taken to prevent cats from licking the application site of dogs that have been treated with this product. Seek
immediate veterinary assistance if this occurs.
Consult your veterinarian before using this product in sick and debilitated animals.
As the product is dangerous to aquatic organisms, treated dogs must under no circumstances be allowed to enter any surface water
for at least 48 hours after treatment.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Avoid contact with skin, eyes or mouth. Do not eat, drink, or smoke during product application.
Wash hands thoroughly after applying the product.
If the product accidentally gets on the skin, immediately wash the area with soap and water.
Individuals with known skin sensitivity may be particularly sensitive to this product.
If the product accidentally gets into the eyes, wash the eyes with plenty of water. If skin or eye symptoms persist, or the product is
accidentally swallowed, seek immediate medical advice and show the doctor the product leaflet.
Treated dogs should not be allowed to play, especially with children, until the application site is dry. To be safe, treat dogs in the
evening, for example. In this case, treated dogs are not allowed to sleep with their owners, especially if they are children.
Special precautions for the disposal of unused product or waste materials, if any
After use, replace the cap on the pipette. Any unused veterinary medicinal product or waste materials derived from such products
should be disposed of in accordance with local requirements.
Other information
Advantix spot-on solution for dogs is a topical ectoparasiticide containing imidacloprid and permethrin.
This combination acts as an insecticide, acaricide, and repellent.
Imidacloprid is an ectoparasiticide belonging to the chloronicotinyl group of compounds. Chemically, it can be classified
as chloronicotinyl nitroguanidine. Imidacloprid is effective against adult fleas and their larval stages. In addition to
its efficacy against adult fleas, the larvicidal efficacy of the substance has also been demonstrated for areas in the animal's habitat.
The product provides repellent (anti-feeding) action against ticks, sandflies, and mosquitoes, thereby preventing
parasite feeding and reducing the risk of transmitting vector-borne diseases (Canine Vector-Borne Disease or
CVBD, such as borreliosis, rickettsiosis, ehrlichiosis, leishmaniasis).
It can be used during pregnancy and lactation.
The solvent in Advantix spot-on solution for dogs may stain certain materials such as leather, fabrics, plastic, and finished surfaces. Allow
the application site to dry before contact with such materials.
Packaging:
Pipettes of 0.4 ml, 1.0 ml, 2.5 ml, 4.0 ml
Blister containing 1, 2, 3, 4 or 6 individual pipettes.
Not all pack sizes may be marketed.
For any information regarding this veterinary medicinal product, please contact the local representative of the marketing authorization holder.
Marketing Authorization Holder
Bayer Animal Health GmbH, D-51368 Leverkusen, Germany
BIOTRIS FLUSH - topical formula with an astringent effect, for cleaning skin and ear canals affected by miconazole-sensitive microorganisms. Can be successfully used for wound care (puncture wounds), lacerations, and abrasions.
Target species: dogs, cats,
Antiseptic formula for topical application.
Astringent cleaning & drying effect on skin and ear canal.
Miconazole = astringent effect
Ceramide III = protection against transepidermal water loss
ACTIVE INGREDIENTS: Miconazole 0.1% (Miconazole Nitrate)
INACTIVE INGREDIENTS: Purified Water, Propylene Glycol, PEG-40
Hydrogenated Castor Oil, Tromethamine, Methylchloroisothiazolinone,
Methylisothiazolinone, Disodium EDTA and N-Octadecanoylphytosphingosine (Ceramide Ill)
DIRECTIONS FOR USE: Apply liberally to the affected area. Use a sterile cotton pad to remove excess solution. Do not allow the animal to lick the area or ingest the product! Apply twice daily or as directed by your veterinarian.
PACKAGING: 473 ml bottle
CAUTION! Product for external veterinary use! Use only on the recommendation of a veterinarian. Keep out of reach of children. Wash hands after use and keep the container properly closed. Follow the instructions for use.
Manufacturer: VETBIOTEK INC, USA
Importer and distributor: CITYVET PET& FARM SRL
BIOSEB FOAM
Salicylic acid +MicroSilver BG = intense antiseptic activity
Ceramide III = protection against transdermal water loss
Indications: foam with keratolytic, keratoplastic, antiseptic effect. pH suitable for dogs, cats, and horses. Fights seborrhea, normalizes keratinization, reduces dandruff.
Target species: dogs, cats, horses
ACTIVE INGREDIENTS: Salicylic acid 2%
INACTIVE INGREDIENTS: Purified Water, Ethyl Lactate, Ordenone, Glycerin, Sodium Alpha Olefin Sulfonate,
Cocamidopropyl Betaine, Fragrance, SDA40B Alcohol, Polysorbate 80, Acrylates Copolymer, Polyquaternium 7,
Methylchloroisothiazolinone, Methylisothiazolinone, N-Octadecanoylphytosphingosine (Ceramide III) and
MicroSilver.
DIRECTIONS FOR USE: shake before use. Brush the coat and apply the foam. Massage until it penetrates the coat and reaches the skin. Do not rinse! Allow to air dry naturally.
Dose the foam according to animal weight:
Under 5 kg BW - 1 pump/ 1 kg BW
6-40 kg BW - 1 pump/ 2 kg BW
Over 40 kg BW - 1 pump/ 2.5 kg BW
For long coats, dosage can be adjusted/increased
For horses - apply topically to affected areas
PACKAGING: 200ml bottle
CAUTION! Product for external veterinary use! Use only on veterinary recommendation. Keep out of reach of children. Wash hands after use and keep the container properly closed. Follow the instructions for use.
Manufacturer: VETBIOTEK INC, USA, www.vetbiotek.com, info@vetbiotek.com
Importer and distributor: CITYVET PET&FARM SRL, www.ctvet.ro, office@ctvet.ro
Indications: This product is recommended for the treatment of older dogs who, due to aging, require an increased intake of substances that can protect them from various age-related disorders. The elements included in the product's composition support the key systems and organs of senior dogs. GeriatiVet strengthens immunity and improves digestion, supports cardiac and joint functions, facilitates fat burning, provides a significant supply of antioxidants and substances that protect the urinary tract, and helps maintain physical condition through substances that prevent muscle mass loss.
Target species: dogs
Administration method:Dogs: 1 tablet / 15-30 kg body weight / day2 tablets < 30 kg body weight / dayTablets can be given whole or crushed, before or with food. The animal must have fresh water available at all times. The correct dosage and administration period depend on the individual needs of the animal and will be determined by a veterinarian.
Ingredients:L-Carnitine 150mg, Lutein 20mg, HMB 250mg, Beta-Glucans, Glucosamine, Alpha-Lipoic Acid, Omega-3 Essential Fatty Acids.
Description:Glucosamine is the most researched and recognized nutrient that helps reduce joint risks in older dogs suffering from osteoarthritis. Glucosamine supports the normal functioning of the urinary tract epithelium and helps reduce chronic urinary tract infections in dogs.Glucan β-1,3/1,6 isolated from the cell wall of Saccharomyces cerevisiae is a polysaccharide whose characteristic components activate the immune system. Consequently, the body is better prepared to counteract potential dangers such as bacterial and viral infections. L-Carnitine plays an important role in the metabolism of long-chain fatty acids and energy production. For these reasons, it is crucial for the proper functioning of the myocardium, especially in older dogs prone to cardiomyopathy risks. Also, due to its ability to accelerate fat burning in cells, L-Carnitine can protect the animal from gaining weight or help it with weight loss diets. Lutein contributes to increasing the dog's immunity by activating cellular and humoral immune responses. It also plays a role in protecting the retina against damage, thus promoting vision health, due to its antioxidant properties and its ability to filter energy from blue light. HMB is a natural derivative of leucine, as is beta-hydroxy-beta-methylbutyrate. It protects the cellular skeleton of muscles against degradation and helps maintain muscle mass, especially in older dogs who are prone to skeletal muscle atrophy. It encourages protein synthesis in skeletal muscles and protects the animal against muscle degradation, regardless of the cause.Omega 3 fatty acids are some of the most important components of the neuron membrane. They protect neurons from disorders and strengthen their basic functions. Also, due to their anti-inflammatory and anti-edemic properties, they contribute to reducing pressure in the glomeruli (renal protection). They are also recognized for their anti-arrhythmic properties.Alpha-lipoic acid is one of the most powerful antioxidants and protects neurons against the damaging effects caused by free radical reactions or disorders occurring due to excessive oxidation of the cell membrane.
Packaging: 45 tablets
Storage conditions: Store in a place protected from moisture and direct sunlight, at temperatures up to 25°C.
Analytical compounds:Proteins 10.21%, Oils and fats 1.46%, Ash (including mineral compounds) 10.59%, Fiber 18.85%, Moisture 4.72%.
Additional information:ATTENTION! For veterinary use only! Keep out of reach of children! Follow the instructions on the packaging.Contact your veterinarian before using or extending the use of this product, as dosage or method of use may change depending on the animal's individual symptoms.
Indications:The product is recommended for treating elderly dogs who, due to aging, need an increased intake of substances that can protect them from various disorders specific to old age. The elements in the product support the key systems and organs of senior dogs. GeriatiVet strengthens immunity and improves digestion, supports cardiac and joint functions, facilitates fat burning, provides a significant intake of antioxidants and substances that protect the urinary tract, and helps maintain physical condition through substances that prevent muscle mass loss.
Target species: dogs
Administration:Dogs: 1 tablet / 7.5 kg body weight / dayTablets can be administered whole or crushed, before or with food. The animal must always have fresh water available. The correct dosage and administration period depend on the individual needs of the animal and will be determined by a veterinarian.
Ingredients:L-Carnitine 75mg, Lutein 10mg, HMB 80mg, Beta-Glucans, Glucosamine, Alpha-lipoic acid, Omega-3 essential fatty acids.
Description:Glucosamine is the most researched and recognized nutrient that helps reduce joint risks in elderly dogs suffering from osteoarthritis. Glucosamine supports the normal functioning of the urinary tract epithelium and helps reduce chronic urinary tract infections in dogs.Beta-1,3/1,6 Glucan isolated from the cell wall of Saccharomyces cerevisiae is a polysaccharide whose active characteristic components activate the immune system. Consequently, the body is better prepared to counteract potential dangers such as bacterial and viral infections.L-Carnitine plays an important role in the metabolism of long-chain fatty acids and in energy production. For these reasons, it is crucial for the proper functioning of the myocardium, especially in older dogs predisposed to the risks of cardiomyopathy. Also, due to the fact that it accelerates fat burning in cells, L-Carnitine can protect the animal from gaining weight or help it in weight loss diets.Lutein contributes to increasing the dog's immunity by activating immune responses at the cellular and humoral levels. It also plays a role in protecting the retina against deterioration, thus promoting healthy vision, due to its antioxidant properties and its ability to filter energy from blue light.HMB is a natural derivative of leucine, as is beta-hydroxy-beta-methylbutyrate. It protects the cellular skeleton of muscles against degradation and helps maintain muscle mass, especially in elderly dogs who are prone to skeletal muscle atrophy. It encourages protein synthesis in skeletal muscles and protects the animal against muscle degradation, regardless of the causes.Omega 3 fatty acids are some of the most important components of the neuron membrane. They protect neurons from damage and strengthen their basic functions. Also, due to their anti-inflammatory and anti-edematous properties, they contribute to reducing pressure in the glomeruli (renal protection). They are also recognized for their anti-arrhythmic properties.Alpha-lipoic acid is one of the most powerful antioxidants and protects neurons against the harmful effects caused by free radical reactions or conditions arising from excessive oxidation of the cell membrane.
Packaging: 45 tablets
Storage conditions: Store in a place away from moisture and direct sunlight, at temperatures up to 25°C.
Analytical compounds:Proteins 10.18%, Oils and fats 1.66%, Ash (including mineral compounds) 7.69%, Fiber 22.99%, Moisture 4.66%.
Additional information: CAUTION! For veterinary use only! Keep out of reach of children! Follow the instructions on the packaging. Contact your veterinarian before using or extending the use of this product, as dosage or method of use may change depending on the animal's individual symptoms.
Liquid anti-parasitic solution for cutaneous application, packaged in single-use pipettes.
PACKAGE LEAFLET FOR Cardboard box with 3 pipettes
Frontline Tri-Act spot-on solution for dogs 20-40 kg
DECLARATION OF THE ACTIVE SUBSTANCES AND OTHER INGREDIENTS
Spot-on solution.
Clear, colourless to brown-yellow solution.
Active substances/Excipients:
See section "dosage for each target species"
TARGET SPECIES
Dogs
Warning!!!
Due to the unique physiology of cats, which are unable to metabolize certain compounds, including permethrin, this veterinary medicinal product can cause convulsions in this species that may be fatal.
In case of accidental exposure, it is recommended to wash the cat with shampoo or soap and urgently seek veterinary advice. To prevent accidental exposure of cats to this product, keep cats separate from treated dogs until the application site is dry.
It is important that cats do not lick the application site of the veterinary medicinal product on dogs. In case of such exposure, immediately seek veterinary advice.
INDICATION(S)
For the treatment and prevention of flea and/or tick infestations when repellent (anti-feeding) activity against sandflies, flies, and/or mosquitoes is required.
For the treatment and prevention of flea infestations with Ctenocephalides felis and the prevention of flea infestations with Ctenocephalides canis. The product kills C. felis fleas on the animal within 24 hours. A single
treatment prevents new flea infestations for 4 weeks. The product can be part of a treatment strategy for the control of flea allergy dermatitis if this diagnosis has
been established by a veterinarian.
The product has repellent efficacy against ticks (Dermacentor reticulatus) starting from 7 days and lasting up to 4 weeks after treatment. However, a single tick may attach and detach within the first 24 hours after infestation.
The product has immediate acaricidal efficacy against Rhipicephalus sanguineus and Ixodes ricinus, but if ticks are present at the time of application, they may not die within the first 48 hours after treatment.
The product has persistent acaricidal efficacy against ticks (Ixodes ricinus, Dermacentor reticulatus, Rhipicephalus sanguineus) for 4 weeks.
The product has repellent (anti-feeding) efficacy for 3 weeks against sandflies (Phlebotomus perniciosus) and for 4 weeks against mosquitoes (Culex pipiens).
The product has persistent insecticidal efficacy against sandflies (Phlebotomus perniciosus) for 3 weeks.
The product repels and kills stable flies (Stomoxys calcitrans) for five weeks.
CONTRAINDICATIONS
Do not use on sick or convalescent animals.
Do not use on cats and rabbits as it may cause adverse reactions and even death.
Do not use in cases of known hypersensitivity to the active substance or to any of the excipients.
ADVERSE REACTIONS
Among the suspected, very rare adverse reactions reported after use were transient reactions
on the skin at the application site (skin discoloration, local alopecia, pruritus, erythema) and generalized pruritus or alopecia. Also reported were hypersalivation, reversible neurological reactions (increased sensitivity to stimuli, hyperactivity, muscle tremor, depression, other neurological reactions) or vomiting.
Slight hypersalivation and vomiting may occur if the product is ingested, if the animal licks the application area.
If you notice any serious reactions or other effects not mentioned in this package leaflet, please inform your veterinary surgeon.
DOSAGE FOR EACH SPECIES, ROUTE(S) AND METHOD OF ADMINISTRATION
Topical application to the skin (spot-on).
The following table defines which pipette should be used depending on the dog's weight:
Active ingredients Excipients
Frontline Tri-Act spot-on solution for dogs Unit volume Fipronil (mg) Permethrin Butylhydroxytoluene
dosed (mg) (E321) (mg)
Very small dogs 2-5kg 0.5 33.8 252.4 0.563
Small dogs 5-10kg 1 67.6 504.8 1.125
Medium dogs 10-20kg 2 135.2 1009.6 2.250
Large dogs 20-40kg 4 270.4 2019.2 4.500
XL dogs 40-60kg 6 405.6 3028.8 6.750
Dogs > 60 kg Use the appropriate combination of pipettes
Treatment regimen
The product should be used following confirmation of infestation or risk of infestation with fleas and/or ticks, simultaneously with the need for repellent (anti-feeding) activity against sandflies and/or mosquitoes and/or flies.
Depending on the recurrence of the risk of infestation with these ectoparasites, treatment repetition can be established. In these cases, the minimum treatment interval is at least 4 weeks.
RECOMMENDATIONS FOR CORRECT ADMINISTRATION
Select the appropriate pipette for the dog's weight. For dogs weighing more than 60 kg, the necessary combination of pipettes should be used to achieve the appropriate amount for the dog's weight.
The product should be applied in two areas where the dog cannot reach, so that it cannot lick the application site. These application sites are one at the base of the neck above the shoulder blades and the other on the midline of the neck between the base of the skull and the shoulder blades.
Remove the blister foil from the package and detach one blister. Use scissors to cut the blister along the dotted line to remove the pipette or fold the marked corner and tear open.
Hold the pipette upright, away from your face or body, cut the tip of the pipette with scissors. Part the dog's fur until the skin is visible. Position the pipette tip on the skin.
Squeeze the pipette and apply approximately half of the content to the midline of the dog's neck, between the base of the skull and the shoulder blades. Repeat the application at the base of the neck, above the shoulder blades, emptying the pipette.
To achieve the best results, ensure that the product is applied directly to the skin and not to the fur.
WITHDRAWAL PERIOD
Not applicable
SPECIAL PRECAUTIONS FOR STORAGE
Keep out of the sight and reach of children.
Store in the original packaging.
Do not store above 25 °C
Do not use after the expiry date stated on the packaging after "EXP". The expiry date refers to the last day of that month.
SPECIAL WARNING(S)
Special warnings for each target species
A single tick may already be attached to the animal or a mosquito or sandfly bite may be present. For this reason, the transmission of pathogens by these arthropods cannot be excluded if conditions are favorable.
The product remains effective against fleas when treated animals occasionally enter water (e.g., swimming, bathing). However, dogs should not be allowed to swim or be shampooed for 48 hours after treatment application.
Avoid frequent swimming or shampooing of treated dogs as this may affect the maintenance of product efficacy.
In order to reduce re-infestation due to the emergence of new fleas, it is recommended that all dogs in the household be treated. Animals living in the same environment should be treated with a veterinary medicinal product suitable for their species.
To reduce the risk of environmental infestation, the use of an additional treatment is recommended
appropriate to the environment in which the animals live, against fleas and their developmental stages.
Special precautions for use in animals
In the absence of specific studies, the use of this product is not recommended for dogs less than 8 weeks of age or weighing less than 2 kg.
Avoid contact of the product with the animal's eyes.
It is very important to ensure that the product is applied to an area where the animal cannot lick the product and also to ensure that animals do not lick each other after
treatment.
Due to the unique physiology of cats, which are unable to metabolize certain compounds, including permethrin, this veterinary medicinal product can cause convulsions in this species that may be fatal.
In case of accidental exposure, it is recommended to wash the cat with shampoo or soap and urgently seek veterinary advice. To prevent accidental exposure of cats to this product, keep cats separate from treated dogs until the application site is dry.
It is important that cats do not lick the application site of the veterinary medicinal product on dogs. In case of such exposure, immediately seek veterinary advice.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
For veterinary use only.
This product may cause skin and eye irritation. Therefore, contact of the product with skin or eyes must be avoided. Do not open the pipette near or towards the face. If accidentally sprayed into the eyes or if eyes become irritated during product administration, immediate thorough washing with water is recommended. If eye irritation persists, seek medical advice.
Persons with known hypersensitivity to fipronil and/or permethrin should avoid contact with this product.
The product is harmful if swallowed. Avoid hand-to-mouth contact. Do not smoke, drink or eat during product application. Wash hands after use. In case of ingestion, rinse mouth with water and seek medical advice if you feel unwell.
As the excipient N-methylpyrrolidone may cause foetotoxicity and teratogenicity following prolonged exposure, pregnant women are advised to wear gloves to avoid contact with the product.
Avoid handling the animal until the application site has dried; also, children should not play with the animals until their fur is dry.
Therefore, it is recommended that animals should not be treated during the day but in the evening, and during the night treated animals should sleep alone, not with owners and especially not with children.
Keep pipettes in their original packaging and once used, empty pipettes should be disposed of immediately in an appropriate manner, to prevent further access.
Other precautions
The product may have adverse effects on aquatic organisms. Treated dogs should not be allowed to swim in watercourses for 2 days after treatment.
Use during pregnancy and lactation
Laboratory studies with fipronil and permethrin did not produce any teratogenic or embryotoxic effects. No studies have been performed with this product on animals during pregnancy or lactation.
N-methylpyrrolidone, an excipient of the veterinary medicinal product, has been shown to have a teratogenic effect in laboratory animals after repeated exposure to high doses.
Use only after a benefit/risk assessment by the veterinary surgeon.
Overdose
Safety for use has been evaluated in healthy adult dogs treated with a dose up to 5 times higher
than the maximum recommended dose (treated 3 times at monthly intervals) and in puppies (8 weeks of age, treated once). Among the known adverse reactions, mild neurological symptoms,
vomiting, and diarrhoea may occur. These symptoms are transient and usually resolve without treatment within 1-2 days. Animals should always be treated with the pipette appropriate for their weight.
SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCT OR WASTE MATERIALS, IF APPLICABLE
Any unused veterinary medicinal product or waste materials derived from such products
should be disposed of in accordance with local requirements.
Do not contaminate lakes, watercourses or drains with this product or empty pipettes.
OTHER INFORMATION
Fipronil is an insecticide and acaricide belonging to the phenylpyrazole family. Fipronil kills fleas within 24
hours, ticks and lice within 48 hours of exposure.
Permethrin belongs to the Type I class of pyrethroids, which are acaricides and insecticides with repellent activity.
Permethrin in the product provides repellent activity against sandflies (>80% for 4 weeks), mosquitoes and ticks.
Dietary supplement for dogs and cats.
Hepato Force is a product designed to support liver function and regeneration. The product stands out with its unique selection of ingredients.
Composition: Gelatin (capsule), soy lecithin, magnesium stearate, hydrolyzed poultry protein.
Nutritional additives per 1 kg: L-250.5 g, L-arginine 164 g, Taurine 164 g, Vitamin B1 (thiamine mononitrate) 594 g, Vitamin B2 (riboflavin) 756 g, Nicotinamide 7.9 g, Calcium D-pantothenate 3.5 g, Vitamin B6 (pyridoxine hydrochloride) 756 g, Biotin (d-biotin) 30.5 mg, Folic acid 180 mg, Vitamin B12 (cyanocobalamin) 1.4 mg, Zinc (zinc bisglycinate) 26.2 g.
Sensory additives: Silybum marianum extract*, titanium dioxide (capsule).
*standardized silymarin content - 80%.
Administration: The recommended daily amount of product to be administered with pet food:
Cats: 1 capsule
Dogs:
<10 kg BW - 1 capsule;
10-25 kg BW - 2 capsules;
25 kg BW - 3 capsules;
If necessary, you can open the capsule and mix the contents with food. If the feeding method is based solely on dry food, the food should be slightly moistened to ensure good adhesion of the capsule contents and its complete intake.
Indications
Eudermic shampoo for dogs and cats. Its effectiveness is characterized by the properties of the active substances in the formula. Functional shampoo.
Target species:
- dogs
- cats
Instructions for use:
- Wet the animal's coat with lukewarm water. Apply the product and massage against the fur growth. After 3-5 minutes, rinse the coat carefully with lukewarm water and then dry.
- Protect the animal's eyes and ears during bathing.
Ingredients:
AMP2041 (peptide), Chlorhexidine digluconate max 0.1%, Tris-EDTA, Ethoxylated Lanolin, Amphoteric surfactants, Purified water
Packaging: 200 ml bottle
Storage conditions:
Store in a place away from moisture and direct sunlight, at temperatures up to 25°C.
Epato 1500 mg is a nutritional supplement recommended for adult and senior cats and dogs, as an adjuvant in primary or secondary liver conditions: acute or chronic hepatitis, degeneration of liver function, food or pharmacological intoxications, and during long-term antibiotic or antifungal therapy.
Composition: Titrated or standardized Silymarin, Mannan-oligosaccharides (activators of the non-specific immune system)
Excipients: Hydrolyzed pork liver (palatability agent), brewer's yeast, microcrystalline cellulose, vegetable oils, lecithin, sodium and calcium, aluminum silicate.
Analytical composition: crude protein 25%; crude fat 5.4%; crude fiber 7.9%; moisture 7%; crude ash 12.6%.
Properties: The mechanisms of action are multiple: it increases the liver's detoxifying power by increasing the availability of glutathione; it increases protein synthesis, resulting in increased basal metabolism and appetite stimulation; it normalizes lipid levels, total lipids, triglycerides, and cholesterol; it reduces the degenerative process caused by inflammation, with the help of flavonoids that intervene in the process of converting arachidonic acid into prostaglandins, inhibiting the COX-2 enzyme; it stimulates the synthesis of superoxide dismutase, which prevents the oxidative degeneration of liver cells; due to its Mannan-oligosaccharide content, in addition to its probiotic action in the intestine, it also blocks the multiplication of pathogenic bacteria and helps eliminate them from the intestine through feces.
It is presented in the form of chewable tablets.
