Amflee 134 MG is an antiparasitic pipette for medium-sized dogs weighing between 10-20 kg, which prevents and treats flea and tick infestations.

1 pipette (1.34 ml) contains:

• Active substance: Fipronil 134 mg.
• Other substances: Butylhydroxyanisole (E320) 0.27 mg Butylhydroxytoluene (E321) 0.13

Used for:

• Treatment and prevention of infestations with fleas (Ctenocephalides spp), ticks (Rhipicephalus spp, Dermacentor spp, Ixodes spp.) and infestations with biting lice Trichodectes canis in dogs.
• The product has a persistent insecticidal efficacy of up to 2 months against fleas and an acaricidal efficacy of up to 4 weeks against ticks.
• The product can be used as part of a treatment strategy for flea allergy dermatitis (FAD), if previously diagnosed by a veterinarian.

Contraindications:

• Do not administer to puppies younger than 8 weeks or weighing less than 2 kg.
• Do not administer to sick animals (systemic diseases, fever) or those in convalescence.
• Do not administer to rabbits due to the risk of severe adverse reactions or even death.
• Do not administer to cats, as it may lead to overdose.
• Do not administer in case of hypersensitivity to the active substance or to any of the excipients.

Precautions:

• Ticks on animals should be removed before using the product to reduce the risk of transmissible diseases.
• The product should be applied in a secluded place where the animal cannot lick itself.
• It is recommended to avoid bathing or immersion in water for 2 days after applying the product and to avoid bathing more frequently than once a week.
• Emollient shampoos can be used before treatment, but when used weekly after product application, they reduce the duration of flea protection to approximately 5 weeks.
• Weekly bathing with medicated shampoo containing 2% chlorhexidine does not affect the efficacy of the product against fleas, as shown in a long-term 6-week study.
• Ticks may appear sporadically. Thus, complete exclusion of infection with diseases in unfavorable conditions is impossible. Generally, ticks will die within 24-48 hours after infestation without feeding on the animal's blood.
• Avoid contact of the product with the animal's eyes.
• Dogs should not be allowed to swim in running water for 2 days after application.
• The product can cause irritation to mucous membranes and eyes. Therefore, avoid contact of the product with the mouth and eyes.
• Persons with known hypersensitivity to insecticides or alcohol should avoid contact with the veterinary medicinal product.
• In case of contact, wash hands with soap and water.
• In case of accidental contact with eyes, wash thoroughly with clean water.
• Wash hands after use.
• Do not touch treated animals and do not let children play with them until the application site has dried. Thus, it is not recommended to apply the treatment during the day, but in the evening before bedtime, and treated animals should not be allowed to sleep with their owners, especially with children.
• Do not smoke, drink or eat while applying the product.

Possible adverse reactions:

• If animals lick themselves, short-term hypersalivation may occur, mainly due to the excipients.
• Extremely rare adverse reactions: transient skin reactions at the application site (discoloration and hair loss, itching and erythema) and generalized itching with alopecia.
• Exceptionally, after use, hypersalivation, reversible neurological symptoms (hyperesthesia, depression, nervous signs), respiratory signs, or vomiting have been observed.

Administration:

• Remove the single-dose pipette from the triplex pouch.
• Hold the single-dose pipette upright, twist and pull off the cap.
• Turn the cap over and place the other end of the cap on the single-dose pipette.
• Push and twist the cap to perforate the seal, then remove the cap from the single-dose pipette.
• Part the animal's hair in the area between the shoulder blades to make the skin visible.
• Place the tip of the single-dose pipette on the skin and squeeze the pipette several times to empty the contents directly onto the skin, in one spot.