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2905 products
SUPERPREMIUM HYPOALLERGENIC FOOD WITH A SINGLE SOURCE OF ANIMAL PROTEIN WAS SPECIFICALLY CREATED FOR DOGS WITH WEIGHT CONTROL ISSUES. THE LOW FAT CONTENT COMBINED WITH A HIGH CONTENT OF DIETARY RABBIT PROTEIN CONTRIBUTES TO MAINTAINING OPTIMAL WEIGHT, WHILE L-CARNITINE STIMULATES METABOLISM AND HELPS BURN FAT. PSYLLIUM CONTRIBUTES TO A GREATER FEELING OF SATIETY AND HELPS CONTROL HUNGER BETWEEN MEALS. THE FORMULAS ARE ENRICHED WITH PROBIOTICS FOR A BALANCED INTESTINAL MICROFLORA AND MILK THISTLE, WHICH SUPPORTS LIVER FUNCTION AND CLEANSES THE BODY OF HARMFUL TOXINS.
Joints & Cartilage - Chondroprotectors support the healthy growth and development of joints, bones, and cartilage.
Composition:
dehydrated rabbit (36%), rice (35%), dried apple pulp (12%), lignocellulose (10%), chicken fat, natural flavor, brewer's yeast, salmon oil (1%), psyllium seeds and husks (0.5%), pea flour, glucosamine (300 mg/kg), fructo-oligosaccharides (230 mg/kg), chondroitin sulfate (230 mg/kg), mannan-oligosaccharides (180 mg/kg), yucca schidigera (180 mg/kg), milk thistle seeds (110 mg/kg), β-glucans (60 mg/kg), dried motherwort (60 mg/kg), dried sea buckthorn (60 mg/kg), Lactobacillus helveticus HA - 122 inactivated probiotics (15x109 cells/kg).
Analytical constituents:
crude protein 27.0%, crude fat 9.0%, moisture 10.0%, crude ash 5.5%, crude fiber 9.5%, calcium 1.2%, phosphorus 0.8%, sodium 0.3%, omega-3 fatty acids 0.3%, omega-6 fatty acids 1.5%, EPA (20:5 n-3) 0.02%, DHA (22:6 n-3) 0.05%.
Nutritional composition:
vitamin A (3a672a) 23000 IU, vitamin D3 (3a671) 1700 IU, vitamin E (3a700) 550 mg, vitamin C (3a312) 350 mg, taurine (3a370) 1500 mg, choline chloride (3a890) 1800 mg, L-carnitine (3a910) 300 mg, vitamin B1 (3a821) 3 mg, vitamin B2 (3a825i) 11 mg, biotin (3a880) 4 mg, folic acid (3a316) 1.4 mg, vitamin B6 (3a831) 3 mg, calcium D-pantothenate (3a841) 30 mg, niacinamide (3a315) 38 mg, vitamin B12 0.12 mg, iodine (3b201) 0.9 mg, organic zinc (3b606) 100 mg, organic manganese (3b504) 45 mg, organic copper (3b406) 20 mg, organic iron (3b106) 88 mg, organic selenium (3b810) 0.18 mg. Contains EU approved antioxidants: tocopherol extract from vegetable oils (1b306(i)), ascorbyl palmitate (1b304) and rosemary extract.
Metabolizable energy:
3110 kcal/kg
Feeding chart:
| Dog's weight (kg) | 5 | 10 | 15 | 20 | 25 | 30 | 40 | 50 | 60 | 70 | 80 | 90 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Weight loss – daily amount (g/day) | 80 | 130 | 180 | 220 | 260 | 310 | 380 | 450 | 510 | 570 | 630 | 690 |
| Weight maintenance – daily amount (g/day) | 90 | 160 | 210 | 260 | 310 | 350 | 430 | 510 | 580 | 660 | 720 | 790 |
SUPER PREMIUM GRAIN-FREE FOOD FOR HEALTHY PUPPY DEVELOPMENT, OPTIMAL GROWTH RATE, AND IMMUNITY SUPPORT. CONTAINS ESSENTIAL CHONDROPROTECTIVES FOR HEALTHY JOINTS AND CARTILAGE. CONTAINS HIGH NUTRITIONAL VALUE PROTEINS AND FATTY ACIDS TO SUPPORT HEALTHY SKIN AND COAT, MENTAL ABILITIES, AND PERFECT PHYSICAL CONDITION. THE GRAIN-FREE FORMULA IS IDEAL FOR DOGS WITH COATS THAT REQUIRE DEMANDING CARE, AS WELL AS FOR DOGS THAT NEED TO MAINTAIN OPTIMAL PHYSICAL CONDITION OR EXHIBIT ADVERSE REACTIONS TO OTHER TYPES OF FOOD. FATTY ACIDS PLAY A CRUCIAL ROLE IN THE HEALTHY DEVELOPMENT OF PUPPIES AND YOUNG DOGS.
Composition:
salmon (52 %) (dehydrated salmon, hydrolyzed salmon), potatoes (26 %), chicken fat, dried apple pulp, salmon oil (3 %), natural flavor, brewer's yeast, hydrolyzed yeast (0.5% - source of inositol and amino acids), pea flour, glucosamine (300 mg/kg), fructo-oligosaccharides (230 mg/kg), chondroitin sulfate (230 mg/kg), mannan-oligosaccharides (180 mg/kg), yucca schidigera (180 mg/kg), milk thistle seeds (110 mg/kg), β-glucans (60 mg/kg), dried motherwort (60 mg/kg), dried sea buckthorn (60 mg/kg), inactivated Lactobacillus helveticus HA – 122 probiotics (15x109 cells/kg).
Analytical constituents:
crude protein 28.0 %, crude fat 15.0 %, moisture level 10.0 %, crude ash 7.0 %, crude fiber 3.2 %, calcium 1.2 %, phosphorus 0.9 %, sodium 0.5 %, omega-3 fatty acids 1.2 %, omega-6 fatty acids 1.9 %, EPA (20:5 n-3) 0.12 %, DHA (22:6 n-3) 0.16 %.
Nutritional composition:
vitamin A (3a672a) 23000 IU, vitamin D3 (3a671) 1700 IU, vitamin E (3a700) 550 mg, vitamin C (3a312) 350 mg, taurine (3a370) 1500 mg, choline chloride (3a890) 1800 mg, L-carnitine (3a910) 300 mg, vitamin B1 (3a821) 3 mg, vitamin B2 (3a825i) 11 mg, biotin (3a880) 4 mg, folic acid (3a316) 1.4 mg, vitamin B6 (3a831) 3 mg, calcium D-pantothenate (3a841) 30 mg, niacinamide (3a315) 38 mg, vitamin B12 0.12 mg, iodine (3b201) 0.9 mg, organic zinc (3b606) 100 mg, organic manganese (3b504) 45 mg, organic copper (3b406) 20 mg, organic iron (3b106) 88 mg, organic selenium (3b810) 0.18 mg. Contains EU approved antioxidants: tocopherol extract from vegetable oils (1b306(i)), ascorbyl palmitate (1b304) and rosemary extract.
Metabolizable energy:
3730 kcal/kg
SUPERPREMIUM, SUSTAINABLE AND ECOLOGICAL FOOD, SPECIALLY DESIGNED FOR DOGS WITH SENSITIVE SKIN. THE HIGH CONTENT OF OMEGA-3 AND OMEGA-6 UNSATURATED FATTY ACIDS CONTRIBUTES TO MAINTAINING A SHINY COAT AND HEALTHY SKIN, STRENGTHENS THE COAT, REDUCES HAIR LOSS, DRYNESS AND DANDRUFF, AND RESTORES SHINE AND LUSTER TO THE HAIR. THE COMBINATION OF INSECT AND FISH PROTEINS HAS EXCELLENT NUTRITIONAL PROPERTIES, REDUCES THE RISK OF FOOD ALLERGIES AND IS SUITABLE FOR DOGS WITH FOOD INTOLERANCE. INSECT PROTEINS HAVE A SIGNIFICANTLY LOWER ECOLOGICAL FOOTPRINT COMPARED TO CONVENTIONAL PROTEINS.
Composition:
dehydrated insects (14%), dehydrated white fish (14%), yellow peas (14%), green peas (14%), dried apple pulp, pea protein, coconut oil (8%), hydrolyzed white fish protein (4%), brewer's yeast, salmon oil (2%), flaxseed (2%), eggshells, pea flour, glucosamine (300 mg/kg), fructo-oligosaccharides (230 mg/kg), chondroitin sulfate (230 mg/kg), mannan-oligosaccharides (180 mg/kg), yucca schidigera (180 mg/kg), milk thistle seeds (110 mg/kg), β-glucans (60 mg/kg), dried motherwort (60 mg/kg), dried sea buckthorn (60 mg/kg), inactivated Lactobacillus helveticus HA - 122 probiotics (15x109 cells/kg).
Analytical constituents:
crude protein 25.0%, crude fat 13.0%, moisture level 10.0%, crude ash 6.5%, crude fiber 3.2%, calcium 1.1%, phosphorus 0.5%, sodium 0.25%, omega-3 fatty acids 0.9%, omega-6 fatty acids 0.75%, EPA (20:5 n-3) 0.25%, DHA (22:6 n-3) 0.2%.
Nutritional additives:
vitamin A (3a672a) 23000 IU, vitamin D3 (3a671) 1700 IU, vitamin E (3a700) 550 mg, vitamin C (3a312) 350 mg, taurine (3a370) 1500 mg, choline chloride (3a890) 1800 mg, L-carnitine (3a910) 300 mg, vitamin B1 (3a821) 3 mg, vitamin B2 (3a825i) 11 mg, biotin (3a880) 4 mg, folic acid (3a316) 1.4 mg, vitamin B6 (3a831) 3 mg, calcium D-pantothenate (3a841) 30 mg, niacinamide (3a315) 38 mg, vitamin B12 0.12 mg, iodine (3b201) 0.9 mg, organic zinc (3b606) 100 mg, organic manganese (3b504) 45 mg, organic copper (3b406) 20 mg, organic iron (3b106) 88 mg, organic selenium (3b810) 0.18 mg. Contains EU approved antioxidants: tocopherol extract from vegetable oils (1b306(i)), ascorbyl palmitate (1b304) and rosemary extract.
Metabolizable energy:
3650 kcal/kg.
Brit Care Dog Sustainable Puppy 3 kg
SUPERPREMIUM, SUSTAINABLE, AND ECOLOGICAL FOOD FOR HEALTHY DIGESTION, STRESS REDUCTION, OPTIMAL PHYSICAL DEVELOPMENT, AND IMMUNE SYSTEM SUPPORT. IDEAL FOR PUPPIES OF ALL BREEDS. CONTAINS EASILY DIGESTIBLE AND NUTRITIONALLY VALUABLE PROTEINS, WITH COMPLETE AMINO ACIDS FOR EXCELLENT MUSCLE TONE AND HEALTHY TISSUES. THE GLUTEN-FREE FORMULA IS SUITABLE FOR ENSURING PROPER DIGESTION IN GROWING PUPPIES. ECOLOGICAL FOOD BASED ON SUSTAINABLE PROTEINS AND INGREDIENTS, WITH A LESS THAN 35% ENVIRONMENTAL IMPACT.
Composition:
chicken (40%) (dehydrated chicken, hydrolyzed chicken), oats (26%), dehydrated insects (14%), chicken fat, dried apple pulp, natural flavor, brewer's yeast, salmon oil (2%), hydrolyzed yeast (0.5% - source of inositol and amino acids), pea flour, glucosamine (300 mg/kg), fructo-oligosaccharides (230 mg/kg), chondroitin sulfate (230 mg/kg), mannan-oligosaccharides (180 mg/kg), yucca schidigera (180 mg/kg), milk thistle seeds (110 mg/kg), β-glucans (60 mg/kg), dried motherwort (60 mg/kg), dried sea buckthorn (60 mg/kg), probiotics Lactobacillus helveticus HA – 122 inactivated (15x109 cells/kg).
Analytical constituents:
crude protein 31.0%, crude fat 19.0%, moisture level 10.0%, crude ash 5.9%, crude fiber 1.5%, calcium 1.4%, phosphorus 1.0%, sodium 0.3%, omega-3 fatty acids 0.5%, omega-6 fatty acids 2.4%, EPA (20:5 n-3) 0.05%, DHA (22:6 n-3) 0.1%.
Nutritional composition:
vitamin A (3a672a) 23000 IU, vitamin D3 (3a671) 1700 IU, vitamin E (3a700) 550 mg, vitamin C (3a312) 350 mg, taurine (3a370) 1500 mg, choline chloride (3a890) 1800 mg, L-carnitine (3a910) 300 mg, vitamin B1 (3a821) 3 mg, vitamin B2 (3a825i) 11 mg, biotin (3a880) 4 mg, folic acid (3a316) 1.4 mg, vitamin B6 (3a831) 3 mg, calcium D-pantothenate (3a841) 30 mg, niacinamide (3a315) 38 mg, vitamin B12 0.12 mg, iodine (3b201) 0.9 mg, organic zinc (3b606) 100 mg, organic manganese (3b504) 45 mg, organic copper (3b406) 20 mg, organic iron (3b106) 88 mg, organic selenium (3b810) 0.18 mg, L-tryptophan (3c440) 4000 mg. Contains EU approved antioxidants: tocopherol extract from vegetable oils (1b306(i)), ascorbyl palmitate (1b304) and rosemary extract.
Metabolizable energy:
4090 kcal/kg.
Vom Feinsten Adult offers you the promise of delicious, healthy, and balanced nutrition at the highest quality level for adult dogs aged 1 to 6 years. The careful selection and quality of the meaty ingredients guarantee a unique culinary delight. This fine pâté provides all the essential nutrients an adult dog needs.
- No artificial colors and preservatives
- Carefully selected meat ingredients
- No soy, no sugar
Ingredients: Turkey (48%), cheese (7%), wheat (4%), calcium carbonate, sodium chloride.
- Protein: 10%
- Fat: 4%
- Crude fiber 0.4%
- Crude ash: 2.5%
- Moisture: 83%
Feeding recommendations:
dog's weight low activity high activity
3 kg 300 g 340 g
5 kg 430 g 500 g
10 kg 725 g 835 g
Metabolizable energy 0.31 MJ / 100g
Vom Feinsten Adult offers you the promise of delicious, healthy, and balanced nutrition at the highest quality level for adult dogs aged 1 to 6 years. The careful selection and quality of the meaty ingredients guarantee a unique culinary delight. This fine pâté provides all the essential nutrients an adult dog needs.
- No artificial colors and preservatives
- Carefully selected meat ingredients
- No soy, no sugar
Ingredients: Turkey (48%), cheese (7%), wheat (4%), calcium carbonate, sodium chloride.
- Protein: 10%
- Fat: 4%
- Crude fiber 0.4%
- Crude ash: 2.5%
- Moisture: 83%
Feeding recommendations:
dog's weight low activity high activity
3 kg 300 g 340 g
5 kg 430 g 500 g
10 kg 725 g 835 g
Metabolizable energy 0.31 MJ / 100g
Vom Feinsten Adult-gourmet offers the promise of delicious, healthy, and balanced nutrition of the highest quality for adult dogs aged 1 to 6 years. The careful selection and quality of the meat ingredients guarantee a unique culinary delight. This fine gourmet pâté provides all the essential nutrients an adult dog needs.
- No artificial colors or preservatives
- Carefully selected meat ingredients
- No soy, no sugar
Ingredients: Turkey (54%), cheese (4%), calcium, sodium chloride.
- Protein: 10.5%
- Fat: 4.5%
- Crude fiber: 0.4%
- Crude ash: 2%
- Moisture: 81%
Feeding recommendations:
Dog's weight g per day
2 - 4 kg 190 - 315 g
5 - 10 kg 370 - 620 g
13 - 20 kg 750 - 1050 g
Metabolizable energy 0.35 MJ / 100g
This replaces the Vom Feinsten Light Lunch Turkey + Cheese 150g product for dogs.
Vom Feinsten Adult Paté with Beef & Turkey Hearts: delicious wet food for choosy dogs
A fine texture, carefully selected meat ingredients, and an exceptional taste! Vom Feinsten Adult Paté with Beef & Turkey Hearts offers adult dogs, aged 1 to 6 years, an unforgettable culinary experience.
These fine pâtés, without grains or soy, provide furry friends with all essential daily nutrients. Vom Feinsten Adult Paté with Beef & Turkey Hearts is a wet food for choosy dogs. Gourmet dogs can choose from a wide range of Vom Feinsten products, with various recipes – including delicious sauces and irresistible gourmet centers.
Ingredients: 63% meat and animal derivatives (35% beef, pork, 8% turkey hearts), minerals.
- Protein: 10.5%
- Fat: 4.5%
- Crude fiber 0.4%
- Crude ash: 2.5%
- Moisture: 81%
Nutritional additives per kg:
-
150 IU Vitamin D₃
-
1 mg Copper (as amino acid)
-
26 mg Zinc sulfate, monohydrate
-
1.7 mg Manganese sulfate, monohydrate
-
0.4 mg Calcium iodate
Dog's weight – Recommended daily amount:
-
2–4 kg: 190–320 g/day
-
5–10 kg: 370–640 g/day
-
12–19 kg: 750–1050 g/day
GranCarno Adult with Duck: delicious wet food for adult dogs
Delicious duck ingredients for a real culinary treat! GranCarno Adult with Duck provides adult dogs (1–6 years) with all the essential nutrients they need. It is a premium wet food that guarantees an authentic and natural taste.
100% fresh and meat-rich ingredients ensure that your dog's bowl will be empty in no time. This tasty wet food is made in Germany and contains no grains, artificial colors or preservatives.
Feeding recommendations
When calculating the ideal amount of dog food, the animal's weight, age, and temperament must be considered.
General feeding guide:
-
2 kg dog: 170 g food per day
-
7 kg dog: 400 g wet food per day
-
16 kg dog: 800 g food per day
-
30 kg large dog: 1200 g food per day
Our specialist veterinarian, Dr. Radicke, can provide personalized recommendations for other weights.
GranCarno – Fresh and rich in meat, just the way dogs like it!
Natural, species-appropriate food – this is the principle of the GranCarno® brand. Fresh and meat-rich ingredients ensure an authentic and unadulterated taste. Delicious wet food that provides your dog with all the essential nutrients. 🐾
- No artificial colors or preservatives
- 100% fresh meat ingredients
- No soy, no grains
Ingredients: 48% pork (heart, liver, lungs, meat), 29% poultry broth, 20% duck (meat, gizzard), minerals, safflower oil.
-
protein: 10.5%
fat: 5%
crude fiber: 0.4%
crude ash: 2.5%
moisture: 79%
Nutritional additives per kg:
-
200 IU Vitamin D₃
-
1.4 mg Manganous sulfate monohydrate
-
25 mg Zinc sulfate monohydrate
-
0.5 mg Copper (II) sulfate pentahydrate
INTEGRA PROTECT is a special dietary food designed for the specific needs of dogs with various health conditions. Our special INTEGRA PROTECT diet for dogs is available for the following conditions:
- Chronic kidney failure
- Food allergies
- Gastrointestinal disorders with acute diarrhea
INTEGRA PROTECT Renal: dry food for dogs with kidney disease
INTEGRA PROTECT Renal is specially formulated to meet the nutritional requirements of dogs with chronic kidney failure. This dry food contains a reduced amount of protein compared to conventional food, which means fewer degradation compounds are formed from protein metabolism. This reduces the strain on the kidneys.
This food also has a reduced phosphorus content, which can slow the progression of kidney disease. Using INTEGRA PROTECT Renal can help extend the dog's lifespan and improve its quality of life.
Ingredients: Rice, maize, poultry protein (dried), poultry fat, beef suet, beet pulp, hydrolyzed poultry protein, poultry liver, salmon oil, flax seeds, dried eggs, fructo-oligosaccharides, calcium carbonate, yeast, potassium chloride, yucca schidigera.
Crude protein: 16%
Fat content: 20%
Crude fibre: 2%
Crude ash: 4.5%
Moisture: 8%
Calcium: 0.7%
Phosphorus: 0.4%
Sodium: 0.2%
Potassium: 0.6%
Linoleic acid: 2%
Nutritional additives per kg:
15,000 IU Vitamin A
1,200 IU Vitamin D3
4.5 mg Copper (II) sulphate pentahydrate
60 mg Zinc oxide
6 mg Manganese oxide
1.6 mg Calcium iodate
Feeding recommendations:
Dog's weight g / day
| 2 - 5 kg | 45 - 75 g |
| 6 - 15 kg | 90 - 175 g |
| 16 - 25 kg | 200 - 280 g |
| 26 - 40 kg | 290 - 365 g |
| 50 - 60 kg | 430 - 495 g |
GranCarno Senior represents delicious, healthy, and balanced nutrition at the highest level for adult dogs aged 7 years and older. Selected fresh and meaty ingredients guarantee the incomparable taste that dogs appreciate so much. GranCarno Senior provides all the essential nutrients a senior dog needs and is specially adapted to the specific requirements of older dogs.
- No artificial colors or preservatives
- 100% fresh meat ingredients
- No soy, no grains
Ingredients: meat and animal derivatives (80% Beef, 9% turkey heart), minerals, vit. D3 200 IU, vit. E 60 mg, vit. D3 200 IU, vit. E 60 mg.
- Protein: 11%
- Fat: 8.5%
- Crude fiber 0.5%
- Crude ash: 1.8%
- Moisture: 78%
Feeding recommendations:
Dog weight low activity normal activity
3 kg 180 g 210 g
5 kg 265 g 300 g
10 kg 450 g 515 g
15 kg 610 g 700 g
20 kg 760 g 870 g
25 kg 895 g 1030 g
30 kg 1025 g 1180 g
40 kg 1275 g 1465 g
60 kg 1725 g 1985 g
Metabolizable energy 0.46 MJ / 100g
GranCarno® Original Adult provides healthy and balanced nutrition at the highest level for adult dogs aged 1 to 6 years. The fresh, meaty ingredients guarantee the incomparable taste that dogs love so much. GranCarno Original Adult provides all the essential nutrients an adult dog needs.
- No artificial colors or preservatives
- 100% fresh meat ingredients
- No soy, no grains
Ingredients: 47% beef (meat, lung, liver, udder, kidney, heart), 15% venison, 6% apple, calcium carbonate.
- Protein: 11%
- Fat: 8.5%
- Crude fiber 0.5%
- Crude ash: 1.8%
- Moisture: 78%
Feeding recommendations:
Dog's weight low activity normal activity
3 kg 180 g 210 g
5 kg 265 g 300 g
10 kg 450 g 515 g
15 kg 610 g 700 g
20 kg 760 g 870 g
25 kg 895 g 1030 g
30 kg 1025 g 1180 g
40 kg 1275 g 1465 g
60 kg 1725 g 1985 g
Metabolizable energy 0.46 MJ / 100g
Liquid antiparasitic solution for cutaneous application, packaged in single-use pipettes.
PACKAGE LEAFLET FOR Cardboard box with 3 pipettes
Frontline Tri-Act spot-on solution for dogs 5-10 kg
DECLARATION OF ACTIVE SUBSTANCES AND OTHER INGREDIENTS
Spot-on solution.
Clear, colorless to brownish-yellow solution.
Active substances/Excipients:
See "dosage for each target species" section
TARGET SPECIES
Dogs
Caution!!!
Due to the unique physiology of cats, which are unable to metabolize certain compounds, including permethrin, this veterinary medicinal product can cause convulsions in this species, which can be fatal.
In case of accidental exposure, it is recommended to wash the cat with shampoo or soap and urgently seek veterinary advice. To prevent accidental exposure of cats to this product, keep cats separate from treated dogs until the application site is dry.
It is important that cats do not lick the site where the veterinary medicinal product has been applied to dogs. In case of such exposure, seek veterinary advice immediately.
INDICATION(S)
For the treatment and prevention of flea and/or tick infestations when repellent (anti-feeding) activity against sandflies, stable flies and/or mosquitoes is required.
For the treatment and prevention of flea infestations by Ctenocephalides felis and the prevention of flea infestations by Ctenocephalides canis. The product kills C. felis fleas on the animal within 24 hours. A single
treatment prevents new flea infestations for 4 weeks. The product can be part of a treatment strategy for the control of flea allergy dermatitis if this diagnosis has
been established by the veterinarian.
The product has repellent efficacy against ticks (Dermacentor reticulatus) starting from 7 days and up to 4 weeks after treatment. However, a single tick may attach and detach within the first 24 hours after infestation.
The product has immediate acaricidal efficacy against Rhipicephalus sanguineus and Ixodes ricinus, but if ticks are present at the time of application, they may not die within the first 48 hours after treatment.
The product has persistent acaricidal efficacy against ticks (Ixodes ricinus, Dermacentor reticulatus, Rhipicephalus sanguineus) for 4 weeks.
The product has repellent (anti-feeding) efficacy for 3 weeks against sandflies (Phlebotomus perniciosus) and for 4 weeks against mosquitoes (Culex pipiens).
The product has persistent insecticidal efficacy against sandflies (Phlebotomus perniciosus) for 3 weeks.
The product repels and kills stable flies (Stomoxys calcitrans) for five weeks.
CONTRAINDICATIONS
Do not use on sick or convalescing animals.
Do not use on cats and rabbits as it may cause adverse reactions and even death.
Do not use in cases of known hypersensitivity to the active substance or to any of the excipients.
ADVERSE REACTIONS
Among the suspected, very rare adverse reactions reported after use, transient reactions have occurred
on the skin at the application site (skin discoloration, local alopecia, pruritus, erythema) and generalized pruritus or alopecia. Hypersalivation, reversible neurological reactions (increased sensitivity to stimuli, hyperactivity, muscle tremors, depression, other neurological reactions) or vomiting have also been reported.
Mild hypersalivation and vomiting may occur if the product is ingested, if the animal licks the application site.
If you notice any serious reactions or other effects not mentioned in this package leaflet, please inform your veterinarian.
DOSAGE FOR EACH SPECIES, ROUTE(S) OF ADMINISTRATION AND METHOD OF ADMINISTRATION
Topical application to the skin (spot-on).
The following table defines which pipette should be used depending on the dog's weight:
Active Ingredients Excipients
Frontline Tri-Act spot-on Volume of unit Fipronil (mg) Permethrin Butylhydroxytoluene
solution for dogs dosed (mg) (E321) (mg)
Very small dogs 2-5kg 0.5 33.8 252.4 0.563
Small dogs 5-10kg 1 67.6 504.8 1.125
Medium dogs 10-20kg 2 135.2 1009.6 2.250
Large dogs 20-40kg 4 270.4 2019.2 4.500
XL dogs 40-60kg 6 405.6 3028.8 6.750
Dogs > 60 kg Use the appropriate combination of pipettes
Treatment schedule
The product should be used after confirmation of infestation or risk of infestation with fleas and/or ticks, simultaneously with the need for repellent (anti-feeding) activity against sandflies and/or mosquitoes and/or stable flies.
Depending on the recurrence of the risk of infestation with these ectoparasites, repeated treatment may also be established. In these cases, the minimum treatment interval is at least 4 weeks.
ADVICE ON CORRECT ADMINISTRATION
Choose the pipette appropriate for the dog's weight. For dogs weighing over 60 kg, the necessary combination of pipettes should be used until the amount appropriate for the dog's weight is reached.
The product should be applied in two areas where the dog cannot reach, so that it cannot lick the application site.
These application sites are one at the base of the neck above the shoulder blades and the other on the midline of the neck between the base of the skull and the shoulder blades.
Remove the blister foil from the package and detach one blister. Use scissors to cut the blister along the dotted line to remove the pipette or fold the marked corner and tear open.
Hold the pipette upright, away from your face or body, cut the tip of the pipette with scissors. Part the dog's fur so that the skin is visible. Position the tip of the pipette on the skin.
Squeeze the pipette and apply approximately half of the content to the midline of the dog's neck, between the base of the skull and the shoulder blades. Repeat the application at the base of the neck, above the shoulder blades, emptying the pipette.
To obtain the best results, make sure to apply the product directly to the skin and not to the fur.
WAITING PERIOD
Not applicable
SPECIAL PRECAUTIONS FOR STORAGE
Keep out of the sight and reach of children.
Store in the original packaging.
Do not store above 25 °C
Do not use after the expiry date stated on the packaging after "EXP". The expiry date refers to the last day of that month.
SPECIAL WARNING(S)
Special warnings for each target species
A single tick or a bite from a mosquito or sandfly may already be present on the animal. For this reason, the transmission of pathogens by these arthropods cannot be excluded, if conditions are favorable.
The product remains effective against fleas when treated animals occasionally enter water (e.g. swimming, bathing). However, dogs should not be allowed to swim and should not be shampooed for 48 hours after treatment.
Avoid swimming or frequent shampooing of treated dogs as this may affect the maintenance of the product's efficacy.
To reduce re-infestation due to the appearance of new fleas, it is recommended that all dogs in the household be treated. Animals living in the same area should be treated with a veterinary medicinal product suitable for their species.
To reduce the risk of environmental infestation, it is recommended to use an additional treatment
appropriate for the environment in which the animals live, against fleas and their developmental stages.
Special precautions for use in animals
In the absence of specific studies, the use of this product is not recommended for dogs less than 8 weeks old or weighing less than 2 kg.
Avoid contact of the product with the animal's eyes.
It is very important to ensure that the product is applied in an area where the animal cannot lick the product and also to ensure that animals do not lick each other after
treatment.
Due to the unique physiology of cats, which are unable to metabolize certain compounds, including permethrin, this veterinary medicinal product can cause convulsions in this species, which can be fatal.
In case of accidental exposure, it is recommended to wash the cat with shampoo or soap and urgently seek veterinary advice. To prevent accidental exposure of cats to this product, keep cats separate from treated dogs until the application site is dry.
It is important that cats do not lick the site where the veterinary medicinal product has been applied to dogs. In case of such exposure, seek veterinary advice immediately.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
For veterinary use only.
This product can cause skin and eye irritation. Therefore, contact of the product with the skin or eyes must be avoided.
Do not open the pipette near or towards the face. If accidentally sprayed into the eyes or if the eyes become irritated during administration of the product, immediate rinsing with plenty of water is recommended. If ocular irritation persists, seek medical advice.
Persons with known hypersensitivity to fipronil and/or permethrin should avoid contact with this product.
The product is harmful if swallowed. Avoid hand-to-mouth contact. Do not smoke, drink or eat during product application. Wash hands after use. In case of ingestion, rinse mouth with water and seek medical advice if you feel unwell.
As the excipient N-methylpyrrolidone can cause fetotoxicity and teratogenicity after prolonged exposure, it is recommended that pregnant women wear gloves to avoid contact with the product.
Avoid handling the animal until the application site is dry; children should also not play with the animals until their fur is dry.
Therefore, it is recommended that animals are not treated during the day but in the evening, and during the night, treated animals should sleep alone, not with owners and especially not with children.
Keep pipettes in the original packaging and once used, empty pipettes must be disposed of immediately in an appropriate manner, to prevent subsequent access.
Other precautions
The product can be harmful to aquatic organisms. Treated dogs should not be allowed to swim in watercourses for 2 days after treatment.
Use during pregnancy and lactation
Laboratory studies with fipronil and permethrin produced no teratogenic or embryotoxic effects. No studies have been conducted with this product on animals during pregnancy or lactation.
N-methylpyrrolidone, an excipient of the veterinary medicinal product, has been shown to have a teratogenic effect in laboratory animals after repeated exposure to high doses.
Use only after a benefit/risk assessment by the veterinarian.
Overdose
Safety of use has been evaluated in healthy adult dogs treated with a dose up to 5 times higher
than the maximum recommended dose (treated 3 times at monthly intervals) and in puppies (8 weeks old, treated once). Known adverse reactions may include mild neurological symptoms,
vomiting and diarrhea. These symptoms are transient and usually disappear without treatment within 1-2 days. Animals should always be treated with the pipette corresponding to their weight.
SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCT OR WASTE, IF APPLICABLE
Any unused veterinary medicinal product or waste derived from the use of such products
must be disposed of in accordance with local requirements.
Do not contaminate lakes, watercourses or drains with this product or empty pipettes.
OTHER INFORMATION
Fipronil is an insecticide and acaricide belonging to the phenylpyrazole family. Fipronil kills fleas within 24 hours, ticks and lice within 48 hours of exposure.
Permethrin belongs to the Type I pyrethroid class, which are acaricides and insecticides with repellent activity.
Permethrin in the product provides repellent activity against sandflies (>80% for 4 weeks), mosquitoes and ticks.
Liquid antiparasitic solution for cutaneous application, packaged in single-dose pipettes.
PACKAGE LEAFLET FOR Cardboard box with 3 pipettes
Frontline Tri-Act spot-on solution for dogs 10-20 kg
DECLARATION OF ACTIVE SUBSTANCES AND OTHER INGREDIENTS
Spot-on solution.
Clear, colourless to brownish-yellow solution.
Active substances/Excipients:
See section "Dosage for each target species"
TARGET SPECIES
Dogs
Caution!!!
Due to the unique physiology of cats, which are unable to metabolize certain compounds, including permethrin, this veterinary medicinal product can cause convulsions in this species that may be fatal.
In case of accidental exposure, it is recommended to wash the cat with shampoo or soap and seek urgent veterinary advice. To prevent accidental exposure of cats to this product, keep cats separate from treated dogs until the application site is dry.
It is important that cats do not lick the application site of the veterinary medicinal product on dogs. In case of such exposure, seek immediate veterinary advice.
INDICATION (INDICATIONS)
For the treatment and prevention of flea and/or tick infestations when repellent (anti-feeding) activity against sandflies, flies, and/or mosquitoes is required.
For the treatment and prevention of flea infestations with Ctenocephalides felis and the prevention of flea infestations with Ctenocephalides canis. The product kills C. felis fleas on the animal within 24 hours. A single
treatment prevents new flea infestation for 4 weeks. The product can be part of the treatment strategy for the control of flea allergy dermatitis if this diagnosis has
been established by a veterinarian.
The product has repellent efficacy against ticks (Dermacentor reticulatus) from 7 days up to 4 weeks after treatment. However, a single tick may attach and detach within the first 24 hours after infestation.
The product has immediate acaricidal efficacy against Rhipicephalus sanguineus and Ixodes ricinus species, but if ticks are present at the time of application, they may not die within the first 48 hours after treatment.
The product has persistent acaricidal efficacy against ticks (Ixodes ricinus, Dermacentor reticulatus, Rhipicephalus sanguineus) for 4 weeks.
The product has repellent (anti-feeding) efficacy for 3 weeks against sandflies (Phlebotomus perniciosus) and for 4 weeks against mosquitoes (Culex pipiens).
The product has persistent insecticidal efficacy against sandflies (Phlebotomus perniciosus) for 3 weeks.
The product repels and kills stable flies (Stomoxys calcitrans) for five weeks.
CONTRAINDICATIONS
Do not use on sick or convalescing animals.
Do not use on cats and rabbits as it may cause adverse reactions and even death.
Do not use in cases of known hypersensitivity to the active substance or to any of the excipients.
ADVERSE REACTIONS
Among the suspected, very rare adverse reactions, transient skin reactions at the application site (skin discolouration, local alopecia, pruritus, erythema) and generalised pruritus or alopecia have been reported after use. Hypersalivation, reversible neurological reactions (increased sensitivity to stimuli, hyperactivity, muscle tremors, depression, other neurological reactions) or vomiting have also been reported.
Mild hypersalivation and vomiting may occur if the product is ingested, for example, if the animal licks the application area.
If you notice any serious reactions or other effects not mentioned in this leaflet, please inform your veterinary surgeon.
DOSAGE FOR EACH SPECIES, ROUTE(S) OF ADMINISTRATION AND METHOD OF ADMINISTRATION
Topical application on the skin (spot-on).
The following table defines which pipette should be used depending on the dog's weight:
Active ingredients Excipients
Frontline Tri-Act spot- Volume of unit Fipronil (mg) Permethrin Butylhydroxytoluene
on for dogs dosed (mg) (E321) (mg)
Very small dogs 2-5kg 0.5 33.8 252.4 0.563
Small dogs 5-10kg 1 67.6 504.8 1.125
Medium dogs 10-20kg 2 135.2 1009.6 2.250
Large dogs 20-40kg 4 270.4 2019.2 4.500
XL dogs 40-60kg 6 405.6 3028.8 6.750
Dogs > 60 kg Use the appropriate combination of pipettes
Treatment regimen
The product should be used after confirmation of infestation or risk of infestation with fleas and/or ticks, simultaneously with the need for repellent (anti-feeding) activity against sandflies and/or mosquitoes and/or flies.
Depending on the recurrence of the risk of infestation with these ectoparasites, repeated treatment may be established. In these cases, the minimum treatment interval is at least 4 weeks.
ADVICE ON CORRECT ADMINISTRATION
Select the appropriate pipette for the dog's weight. For dogs weighing more than 60 kg, the necessary combination of pipettes should be used until the appropriate quantity for the dog's weight is reached.
The product should be applied in two areas where the dog cannot reach, so that it cannot lick the application site. These application sites are one at the base of the neck above the shoulder blades and the other on the midline of the neck between the base of the skull and the shoulder blades.
Remove the blister foil from the packaging and tear off one blister. Use scissors to cut the blister along the dotted line to remove the pipette or fold the marked corner and tear open.
Hold the pipette upright, away from your face or body, cut the tip of the pipette with scissors. Part the dog's fur until the skin is visible. Position the pipette tip on the skin.
Squeeze the pipette and apply approximately half of the content to the midline of the dog's neck, between the base of the skull and the shoulder blades. Repeat the application at the base of the neck, above the shoulder blades, emptying the pipette.
For best results, ensure the product is applied directly to the skin and not to the fur.
WITHDRAWAL PERIOD
Not applicable
SPECIAL PRECAUTIONS FOR STORAGE
Keep out of the sight and reach of children.
Store in the original packaging.
Do not store above 25 °C
Do not use after the expiry date stated on the packaging after "EXP". The expiry date refers to the last day of that month.
SPECIAL WARNING(S)
Special warnings for each target species
A single tick or a mosquito or sandfly bite may already be present on the animal. Therefore, the transmission of pathogens by these arthropods cannot be excluded if conditions are favourable.
The product remains effective against fleas when treated animals occasionally enter water (e.g., swimming, bathing). However, dogs should not be allowed to swim or be shampooed for 48 hours after treatment application.
Avoid swimming or frequent shampooing of treated dogs as this may affect the maintenance of product efficacy.
In order to reduce re-infestation due to the emergence of new fleas, it is recommended that all dogs in the household be treated. Animals living in the same environment should be treated with a veterinary medicinal product appropriate for their species.
To reduce the risk of environmental infestation, it is recommended to use an additional appropriate treatment for the environment in which the animals live, against fleas and their developmental stages.
Special precautions for use in animals
In the absence of specific studies, the use of this product is not recommended for dogs less than 8 weeks old or weighing less than 2 kg.
Avoid contact of the product with the animal's eyes.
It is very important to ensure that the product is applied in an area where the animal cannot lick the product, and also to ensure that animals do not lick each other after
treatment.
Due to the unique physiology of cats, which are unable to metabolize certain compounds, including permethrin, this veterinary medicinal product can cause convulsions in this species that may be fatal.
In case of accidental exposure, it is recommended to wash the cat with shampoo or soap and seek urgent veterinary advice. To prevent accidental exposure of cats to this product, keep cats separate from treated dogs until the application site is dry.
It is important that cats do not lick the application site of the veterinary medicinal product on dogs. In case of such exposure, seek immediate veterinary advice.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
For veterinary use only.
This product may cause skin and eye irritation. Consequently, contact of the product with skin or eyes should be avoided. Do not open the pipette near or towards the face. If accidentally sprayed into the eyes or if eyes become irritated during administration of the product, immediate abundant washing with water is recommended. If ophthalmic irritation persists, seek medical advice.
Persons with known hypersensitivity to fipronil and/or permethrin should avoid contact with this product.
The product is harmful if swallowed. Avoid hand-to-mouth contact. Do not smoke, drink or eat during product application. Wash hands after use. In case of swallowing, rinse mouth with water and seek medical advice if you feel unwell.
As the excipient N-methylpyrrolidone may cause foetotoxicity and teratogenicity following prolonged exposure, it is recommended that pregnant women wear gloves to avoid contact with the product.
Avoid handling the animal until the application site has dried. Children should also not play with the animals until the fur is dry.
Therefore, it is recommended that animals are not treated during the day but in the evening, and treated animals should sleep alone during the night, not with owners and especially not with children.
Store pipettes in the original packaging, and once used, empty pipettes should be disposed of immediately in an appropriate manner to prevent subsequent access.
Other precautions
The product may adversely affect aquatic organisms. Treated dogs should not be allowed to swim in watercourses for 2 days after treatment.
Use during pregnancy and lactation
Laboratory studies with fipronil and permethrin have not produced any teratogenic or embryotoxic effects. No studies have been conducted with this product on animals during pregnancy or lactation.
N-methylpyrrolidone, an excipient of the veterinary medicinal product, has been shown to have a teratogenic effect in laboratory animals after repeated exposure to high doses.
Use only based on a benefit/risk assessment by the veterinary surgeon.
Overdose
Safety of use was evaluated in healthy adult dogs treated with a dose up to 5 times the maximum recommended dose (treated 3 times at monthly intervals) and in puppies (8 weeks old, treated once). Known adverse reactions may include mild neurological symptoms,
vomiting and diarrhoea. These symptoms are transient and usually resolve without treatment within 1-2 days. Animals should always be treated with the pipette appropriate for their weight.
SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCT OR WASTE MATERIALS, IF ANY
Any unused veterinary medicinal product or waste materials derived from such products
should be disposed of in accordance with local requirements.
Do not contaminate ponds, watercourses or ditches with this product or empty pipettes.
OTHER INFORMATION
Fipronil is an insecticide and acaricide belonging to the phenylpyrazole family. Fipronil kills fleas within 24 hours,
ticks and lice within 48 hours of exposure.
Permethrin belongs to the Type I pyrethroid class, which are acaricides and insecticides with repellent activity.
Permethrin in the product provides repellent activity against sandflies (>80% for 4 weeks), mosquitoes and ticks.
Liquid antiparasitic solution for cutaneous application packaged in single-use pipettes.
PACKAGE LEAFLET FOR Cardboard box with 3 pipettes
Frontline Tri-Act spot-on solution for dogs 40-60 kg
STATEMENT OF THE ACTIVE SUBSTANCES AND OTHER INGREDIENTS
Spot-on solution.
Clear, colourless to yellow-brown solution.
Active substances/Excipients:
See section "dosage for each target species"
TARGET SPECIES
Dogs
Caution!!!
Due to the unique physiology of cats, which are unable to metabolise certain compounds, including permethrin, this veterinary medicinal product can cause convulsions in this species, which can be fatal.
In case of accidental exposure, it is recommended to wash the cat with shampoo or soap and seek urgent veterinary advice. To prevent accidental exposure of cats to this product, keep cats separate from treated dogs until the application site is dry.
It is important that cats do not lick the site where the veterinary medicinal product has been applied to dogs. In case of such exposure, seek veterinary advice immediately.
INDICATION (INDICATIONS)
For the treatment and prevention of flea and/or tick infestations when repellent (anti-feeding) activity against sandflies, flies and/or mosquitoes is required.
For the treatment and prevention of infestations with fleas Ctenocephalides felis and prevention of infestations with fleas Ctenocephalides canis. The product kills C. felis fleas on the animal within 24 hours. A single
treatment prevents new flea infestation for 4 weeks. The product can be part of a treatment strategy for the control of flea allergy dermatitis if this diagnosis has been
established by the veterinarian.
The product has repellent efficacy against ticks (Dermacentor reticulatus) starting from 7 days and up to 4 weeks after treatment. However, a single tick can attach and detach within the first 24 hours after infestation.
The product has immediate acaricidal efficacy against Rhipicephalus sanguineus and Ixodes ricinus species, but if ticks are present at the time of application, they may not die within the first 48 hours after treatment.
The product has persistent acaricidal efficacy against ticks (Ixodes ricinus, Dermacentor reticulatus, Rhipicephalus sanguineus) for 4 weeks.
The product has repellent (anti-feeding) efficacy for 3 weeks against sandflies (Phlebotomus perniciosus) and for 4 weeks against mosquitoes (Culex pipiens).
The product has persistent insecticidal efficacy against sandflies (Phlebotomus perniciosus) for 3 weeks.
The product repels and kills stable flies (Stomoxys calcitrans) for five weeks.
CONTRAINDICATIONS
Do not use on sick or convalescing animals.
Do not use on cats and rabbits as it can cause adverse reactions and even death.
Do not use in case of known hypersensitivity to the active substance or to any of the excipients.
ADVERSE REACTIONS
Among the very rare suspected adverse reactions, transient skin reactions at the application site (skin discoloration, local alopecia, pruritus, erythema) and generalized pruritus or alopecia have been reported after use. Hypersalivation, reversible neurological reactions (increased sensitivity to stimuli, hyperactivity, muscle tremors, depression, other neurological reactions) or vomiting have also been reported.
Mild hypersalivation and vomiting may occur if the product is ingested, if the animal licks the application site.
If you notice any serious reactions or other effects not mentioned in this leaflet, please inform your veterinarian.
DOSAGE FOR EACH SPECIES, ROUTE(S) OF ADMINISTRATION AND METHOD OF ADMINISTRATION
Topical administration to the skin (spot-on).
The following table defines which pipette should be used depending on the dog's weight:
Active ingredients Excipients
Frontline Tri-Act spot-on solution for dogs. Volume of dosed unit. Fipronil (mg) Permethrin (mg) Butylated hydroxytoluene (E321) (mg)
Very small dogs 2-5kg 0.5 33.8 252.4 0.563
Small dogs 5-10kg 1 67.6 504.8 1.125
Medium dogs 10-20kg 2 135.2 1009.6 2.250
Large dogs 20-40kg 4 270.4 2019.2 4.500
XL dogs 40-60kg 6 405.6 3028.8 6.750
Dogs > 60 kg Use the appropriate combination of pipettes
Treatment scheme
The product should be used after confirmation of infestation or risk of infestation with fleas and/or ticks, along with the need for repellent (anti-feeding) activity against sandflies and/or mosquitoes and/or flies.
Depending on the recurrence of infestation risk with these ectoparasites, treatment repetition can also be established. In these cases, the minimum treatment interval is at least 4 weeks.
RECOMMENDATIONS FOR CORRECT ADMINISTRATION
Select the appropriate pipette for the dog's weight. For dogs weighing more than 60 kg,
the necessary combination of pipettes should be used until the appropriate quantity for the dog's weight is reached.
The product should be applied in two areas where the dog cannot reach, so that it cannot lick the application site.
These application sites are one at the base of the neck above the shoulder blades and the other on the midline of the neck between the base of the skull and the shoulder blades.
Remove the blister foil from the packaging and detach one blister. Use scissors to cut the blister along the dotted line to remove the pipette, or fold the marked corner and tear it open.
Hold the pipette upright, away from your face or body, and cut the tip of the pipette with scissors. Part the dog's fur until the skin is visible. Position the tip of the pipette on the skin.
Squeeze the pipette and apply approximately half of the content to the midline of the dog's neck, between the base of the skull and the shoulder blades. Repeat the application at the base of the neck, above the shoulder blades, emptying the pipette.
To achieve the best results, ensure that the product is applied directly to the skin and not to the fur.
WITHDRAWAL PERIOD
Not applicable
SPECIAL PRECAUTIONS FOR STORAGE
Keep out of the sight and reach of children.
Store in the original packaging.
Do not store above 25 °C.
Do not use after the expiry date stated on the packaging after "EXP". The expiry date refers to the last day of that month.
SPECIAL WARNING(S)
Special warnings for each target species
A single tick or a bite from a mosquito or sandfly may already be present on the animal. For this reason, the transmission of pathogens by these arthropods cannot be excluded if conditions are favourable.
The product remains effective against fleas when treated animals occasionally enter water (e.g. swimming, bathing). However, dogs should not be allowed to swim or be shampooed for 48 hours after treatment application.
Avoid swimming or frequent shampooing of treated dogs as this may affect the maintenance of product efficacy.
To reduce re-infestation due to the appearance of new fleas, it is recommended that all dogs in the household be treated. Animals living in the same area should be treated with a veterinary medicinal product suitable for their species.
To reduce the risk of environmental infestation, it is recommended to use additional appropriate treatment
for the animals' environment, against fleas and their developmental stages.
Special precautions for use in animals
In the absence of specific studies, the use of this product is not recommended for dogs younger than 8 weeks or weighing less than 2 kg.
Avoid contact of the product with the animal's eyes.
It is very important to ensure that the product is applied in an area where the animal cannot lick the product, and also to ensure that animals do not lick each other after
treatment.
Due to the unique physiology of cats, which are unable to metabolise certain compounds, including permethrin, this veterinary medicinal product can cause convulsions in this species, which can be fatal.
In case of accidental exposure, it is recommended to wash the cat with shampoo or soap and seek urgent veterinary advice. To prevent accidental exposure of cats to this product, keep cats separate from treated dogs until the application site is dry.
It is important that cats do not lick the site where the veterinary medicinal product has been applied to dogs. In case of such exposure, seek veterinary advice immediately.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
For veterinary use only.
This product may cause skin and eye irritation. Therefore, contact of the product with skin or eyes should be avoided. Do not open the pipette near or towards the face. If accidentally sprayed into the eyes or if the eyes become irritated during product administration, immediate thorough washing with water is recommended. If eye irritation persists, seek medical advice.
Persons with known hypersensitivity to fipronil or/and permethrin should avoid contact with this product.
The product is harmful if swallowed. Avoid hand-to-mouth contact. Do not smoke, drink or eat while applying the product. Wash hands after use. In case of ingestion, rinse mouth with water and seek medical advice if you feel unwell.
As the excipient N-methylpyrrolidone may cause foetotoxicity and teratogenicity following prolonged exposure, pregnant women are advised to wear gloves to avoid contact with the product.
Avoid handling the animal until the application site is dry; children should also not play with the animals until the fur is dry.
Therefore, it is recommended that animals are not treated during the day but in the evening, and that treated animals sleep alone during the night, not with their owners and especially not with children.
Keep pipettes in the original packaging and once used, empty pipettes should be disposed of immediately in an appropriate manner to prevent subsequent access.
Other precautions
The product may be harmful to aquatic organisms. Treated dogs should not be allowed to swim in watercourses for 2 days after treatment.
Use during pregnancy and lactation
Laboratory studies with fipronil and permethrin produced no teratogenic or embryotoxic effects. No studies have been conducted with this product on animals during pregnancy or lactation.
N-methylpyrrolidone, an excipient of the veterinary medicinal product, has been shown to have a teratogenic effect in laboratory animals after repeated exposure to high doses.
Use only after a benefit/risk assessment by the veterinarian.
Overdose
Safety of use has been evaluated in healthy adult dogs treated with a dose up to 5 times higher than the maximum recommended dose (treated 3 times at monthly intervals) and in puppies (8 weeks old, treated once). Known adverse reactions may include mild neurological symptoms, vomiting and diarrhoea. These symptoms are transient and usually disappear without treatment within 1-2 days. Animals should always be treated with the pipette corresponding to their weight.
SPECIAL PRECAUTIONS FOR THE DISPOSAL OF UNUSED PRODUCT OR WASTE, IF APPLICABLE
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products
should be disposed of in accordance with local requirements.
Do not contaminate lakes, watercourses or drains with this product or empty pipettes.
OTHER INFORMATION
Fipronil is an insecticide and acaricide belonging to the phenylpyrazole family. Fipronil kills fleas in 24
hours, ticks and lice in 48 hours after exposure.
Permethrin belongs to type I pyrethroids, which are acaricides and insecticides with repellent activity.
Permethrin in the product provides repellent activity against sandflies (>80% for 4 weeks), mosquitoes and ticks.
Advantix is an external antiparasitic product containing imidacloprid and permethrin, and is very effective in treating flea and tick infestations for one month after a single application.
Composition
Each dose (pipette) contains:
| Pipette | Imidacloprid | Permethrin | E321 | |
| Advantix spot-on solution for dogs up to 4 kg | 0.4 ml | 40 mg | 200 mg | 0.4 mg |
| Advantix spot-on solution for dogs from 4 kg to 10 kg | 1.0 ml | 100 mg | 500 mg | 1.0 mg |
| Advantix spot-on solution for dogs from 10 kg to 25 kg | 2.5 ml | 250 mg | 1250 mg | 2.5 mg |
| Advantix spot-on solution for dogs over 25 kg | 4.0 ml | 400 mg | 2000 mg | 4.0 mg |
Excipients: Butylated hydroxytoluene 1.0 mg/ml (E321, as antioxidant):
Indications
For the treatment and prevention of flea infestation (Ctenocephalides canis, Ctenocephalides felis).
Fleas on the dog are killed within one day after treatment. One treatment prevents future flea infestations for four weeks. The product
can be used as part of a treatment strategy for flea allergy dermatitis (FAD).
The product has acaricidal and repellent activity for up to four weeks (Rhipicephalus sanguineus, Ixodes
ricinus) or three weeks (Dermacentor reticulatus) against tick infestations.
Ticks already present on the dog may not be killed within two days after treatment and may remain attached and visible. Therefore, it is
recommended to remove ticks present on the dog at the time of treatment to prevent them from attacking and feeding on blood.
One treatment provides repellent (anti-feeding) action against sandflies for two weeks (Phlebotomus papatasi) or three
weeks (Phlebotomus perniciosus) against mosquitoes for two (Aedes aegypti) and four (Culex pipiens) weeks and for stable flies
(Stomoxys calcitrans) for four weeks.
Sandflies Phlebotomus perniciosus 3 weeks
Phlebotomus papatasi 2 weeks
Mosquitoes Aedes aegypti 2 weeks
Culex pipiens 4 weeks
Stable fly Stomoxys calcitrans 4 weeks
Contraindications
In the absence of available data, the product should not be used on puppies younger than 7 weeks.
Do not use in cases of known hypersensitivity to the active substances.
Do not use on cats.
Adverse reactions
Rarely, transient dermal sensitivity (with increased pruritus, alopecia and erythema at the application site) or apathy may occur.
Poisoning of dogs after accidental ingestion may occur in rare cases. In these cases, neurological signs such as
tremors and apathy may also occur. Symptomatic treatment should be applied under the supervision of a veterinarian. There is no specific antidote.
If you notice any serious reactions or other effects not mentioned in this leaflet, please inform your veterinarian.
Target species
Dogs.
Dosage for each species, route(s) of administration and method of administration
Dosing scheme:
The minimum recommended dose is: 10 mg/kg body weight (b.w.) imidacloprid and 50 mg/kg body weight (b.w.) permethrin, equivalent to
0.1ml/kg b.w. Advantix spot-on solution for dogs.
Dog weight (kg) Pipette size to be used Volume (ml) Imidacloprid (mg/kg b.w.) Permethrin (mg/kg b.w.)
>25 kg - 40 kg Advantix spot-on solution for dogs over 25 kg 4.0 ml 10 - 16 50 - 80
> 40 kg, the appropriate combination of pipettes should be used
| Dog weight (kg) | Pipette size to be used | Volume (ml) | Imidacloprid (mg/kg b.w.) | Permethrin (mg/kg b.w.) |
| <=4 kg | Advantix spot-on solution for dogs up to 4 kg | 0.4 ml | minimum 10 | minimum 50 |
| >4 kg - 10 kg | Advantix spot-on solution for dogs from 4 kg to 10 kg | 1.0 ml | 10 - 25 | 50 - 125 |
| >10 kg - 25 kg | Advantix spot-on solution for dogs from 10 kg to 25 kg | 2.5 ml | 10 - 25 | 50 - 125 |
| >25 kg - 40 kg | Advantix spot-on solution for dogs over 25 kg | 4.0 ml | 10 - 16 | 50 - 80 |
| > 40 kg | the appropriate combination of pipettes should be used |
To reduce re-infestations with new fleas, it is recommended that all dogs in a household be treated. Other pets in
the same family or household must be treated with appropriate products. For fleas originating from the animal's environment,
the additional use of an appropriate product for the treatment against adult fleas and their developmental stages is recommended. The product is active even if the animal is wet. However, prolonged exposure to water should be avoided. In case of prolonged exposure
to water, the efficacy of the product decreases. Even in this case, it should not be treated more frequently than once a week. If it is
necessary to shampoo the animal, it is advisable to apply Advantix spot-on solution for dogs after two weeks
to ensure the efficacy of the product.
Method of administration.
Remove one pipette from the package. Hold the pipette upright, twist and remove the cap. Turn the cap upside down and use it to break the seal of the pipette (by twisting and pressing on the seal, as shown in the photo).
For dogs weighing 10 kg or less:
With the dog standing, part the hair between the shoulder blades until the skin is visible. Apply the tip of the pipette directly to the skin and
squeeze firmly several times to empty the contents of the pipette. Apply only to unbroken skin.
For dogs weighing more than 10 kg:
With the dog standing, the entire contents of the Advantix spot-on solution for dogs pipette will be applied evenly in four places,
starting between the shoulder blades and extending to the base of the tail. At each site, part the hair until the skin is visible. Apply the tip of the pipette to the skin and
gently squeeze to release some of the solution onto the skin.
Recommendations for correct administration
For external use only.
Apply only to unbroken skin.
Do not apply a large amount of solution in one place as it may run down the sides of the dog.
Withdrawal period
Not applicable.
Special precautions for storage
Keep out of the sight and reach of children.
Do not freeze.
After opening the aluminum pouch, store in a dry place and do not store above 30°C.
The abbreviation used for the expiry date on the label, pipette and pouch is EXP.
Special precautions for use in animals
The contents of the pipette must not come into contact with the eyes and mouth of the treated dog.
Pay attention to the correct administration of the product as described in the "Method of administration" section. In particular, oral ingestion
by licking the application site or contact with other animals should be avoided.
Do not use on cats.
This product is highly toxic to cats and can cause death due to the physiological peculiarities of cats
who are unable to metabolize certain compounds, including permethrin. To prevent accidental exposure of
cats to this product, treated dogs should be kept separate from cats after treatment until the application site is dry.
Measures should be taken to ensure that cats do not lick the application site of dogs that have been treated with this product. Seek
immediate veterinary assistance if this happens.
Consult your veterinarian before using this product on sick and debilitated animals.
As the product is dangerous to aquatic organisms, treated dogs must not be allowed to enter any surface water
for at least 48 hours after treatment.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
Avoid contact with skin, eyes or mouth. Do not eat, drink or smoke during product application.
Wash hands thoroughly after product application.
If the product accidentally gets on the skin, wash the area immediately with soap and water.
People with known skin sensitivity may be particularly sensitive to this product.
If the product accidentally gets into the eyes, wash the eyes with plenty of water. If skin or eye symptoms persist, or the product is
accidentally swallowed, seek immediate medical advice and show the product leaflet to the doctor.
Treated dogs should not be allowed to play, especially with children, until the application site is dry. To be safe, treat dogs, for
example, in the evening. In this case, treated dogs are not allowed to sleep with their owners, especially if they are children.
Special precautions for the disposal of unused product or waste materials, if any
After use, replace the cap on the pipette. Any unused veterinary medicinal product or waste material derived from the use of such
products should be disposed of in accordance with local requirements.
Other information
Advantix spot-on solution for dogs is a topical ectoparasiticide containing imidacloprid and permethrin.
This combination acts as an insecticide, acaricide and repellent.
Imidacloprid is an ectoparasiticide belonging to the chloronicotinyl group of compounds. Chemically, it can be classified
as chloronicotinyl nitroguanidine. Imidacloprid is effective against adult fleas and their larval stages. In addition to
its efficacy against adult fleas, the larvicidal efficacy of the substance has also been demonstrated for sites in the animal's habitat.
The product provides repellent (anti-feeding) action against ticks, sandflies and mosquitoes, thereby preventing
parasite blood feeding and reducing the risk of transmission of vector-borne diseases (Canine Vector-Borne Disease or
CVBD, such as borreliosis, rickettsiosis, ehrlichiosis, leishmaniasis).
It can be used during gestation and lactation.
The solvent in Advantix spot-on solution for dogs may stain certain materials such as leather, fabrics, plastic and finished surfaces. Allow
the application site to dry before contact with such materials.
Packaging:
Pipettes of 0.4 ml, 1.0 ml, 2.5 ml, 4.0 ml
Blister containing 1, 2, 3, 4 or 6 individual pipettes.
Not all package sizes may be marketed.
For any information regarding this veterinary medicinal product, please contact the local representative of the marketing authorisation holder.
Marketing Authorisation Holder
Bayer Animal Health GmbH, D-51368 Leverkusen, Germany
GranCarno® Original Adult provides delicious, healthy and balanced nutrition at the highest level for adult dogs aged 1 to 6 years. The fresh, meat-based ingredients guarantee the incomparable taste that dogs love so much. GranCarno Original Adult provides all the essential nutrients an adult dog needs.
- No artificial colors or preservatives
- 100% fresh meat ingredients
- No soy, no grains
Ingredients: 58% beef (heart, meat, lung, liver, udder, kidney), 10% rabbit meat, 0.5% parsley.
- Protein: 11%
- Fat: 7.5%
- Crude fiber: 0.5%
- Crude ash: 1.8%
- Moisture: 78%
Feeding recommendations:
Dog's weight low activity normal activity
3 kg 180 g 210 g
5 kg 265 g 300 g
10 kg 450 g 515 g
15 kg 610 g 700 g
20 kg 760 g 870 g
25 kg 895 g 1030 g
30 kg 1025 g 1180 g
40 kg 1275 g 1465 g
60 kg 1725 g 1985 g
Metabolizable energy 0.46 MJ / 100g
GranCarno® Original Adult provides delicious, healthy and balanced nutrition at the highest level for adult dogs aged 1 to 6 years. The fresh, meat-based ingredients guarantee the incomparable taste that dogs love so much. GranCarno Original Adult provides all the essential nutrients an adult dog needs.
- No artificial colors or preservatives
- 100% fresh meat ingredients
- No soy, no grains
Ingredients: 58% beef (heart, meat, lung, liver, udder, kidney), 10% rabbit meat, 0.5% parsley.
- Protein: 11%
- Fat: 7.5%
- Crude fiber: 0.5%
- Crude ash: 1.8%
- Moisture: 78%
Feeding recommendations:
Dog's weight low activity normal activity
3 kg 180 g 210 g
5 kg 265 g 300 g
10 kg 450 g 515 g
15 kg 610 g 700 g
20 kg 760 g 870 g
25 kg 895 g 1030 g
30 kg 1025 g 1180 g
40 kg 1275 g 1465 g
60 kg 1725 g 1985 g
Metabolizable energy 0.46 MJ / 100g
GranCarno Senior provides delicious, healthy, and balanced nutrition at the highest level for adult dogs aged 7 years and older. Selected fresh, meaty ingredients guarantee the incomparable taste that dogs love so much. GranCarno Senior offers all the essential nutrients a senior dog needs and is specially adapted to the specific requirements of older dogs.
- No artificial colors or preservatives
- 100% fresh meat ingredients
- No soy, no grains
Ingredients: meat and animal derivatives (80% Beef, 9% turkey heart), minerals, vit. D3 200 IU, vit. E 60 mg, vit. D3 200 IU, vit. E 60 mg.
- Protein: 11%
- Fat: 8.5%
- Crude fiber: 0.5%
- Crude ash: 1.8%
- Moisture: 78%
Feeding recommendations:
Dog weight low activity normal activity
3 kg 180 g 210 g
5 kg 265 g 300 g
10 kg 450 g 515 g
15 kg 610 g 700 g
20 kg 760 g 870 g
25 kg 895 g 1030 g
30 kg 1025 g 1180 g
40 kg 1275 g 1465 g
60 kg 1725 g 1985 g
Metabolizable energy 0.46 MJ / 100g
Combined action: diuretic, antilithic, and urinary acidifier.
Complete formula with 9 active ingredients that work synergistically.
For short-term management of FLUTD, promotes struvite dissolution, prevents their recurrence, support in case of mild urinary infections.
Ingredients:
Vaccinium macrocarpon 100mg, Taraxacum officinale 50 mg, vitamin C 60 mg. Arctostaphylos uva-ursi 200 mg, Phyllantus niruri 150 mg, Althaea officinalis 100 mg, L-Methionine 100 mg, Zea mays 60 mg, Olea europea 50 mg.
Administration method:
1 tab/ 10 kg BW/ daily
Dietary supplement for supporting renal functions in cases of chronic kidney disease in dogs and cats.
Dialix Lespedeza PLUS 15 contains:
Lespedeza 300mg - increases diuresis and reduces uremia
CaCO3 450mg - reduces enteric phosphorus absorption.
Contains flavonoids that produce renal vasodilation and stimulate renal parenchyma.
Suitable for long-term use.
Directions for use:
1 tab/ 5 kg BW/ every 12 h
Dietary supplement for supporting renal function in chronic kidney disease in dogs and cats.
Lespedeza capitata (100 mg in DL 5) - increases diuresis and reduces uremia.
Contains flavonoids that cause renal vasodilation and stimulate the renal parenchyma.
Very safe: subacute toxicity tests (5x 30 days) and chronic toxicity tests (5x 90 days) did not produce changes in weight, nor clinical, hematological or histopathological changes.
Ideal for prolonged management of kidney conditions.
Suitable for long-term use.
Administration:
1 tablet/ 1 kg BW/ every 12 h
Indications: Otologic gel with eudermic action, dedicated to dogs and cats.
Benefits:
- improves the physiological condition of the skin
- combats the appearance of irritations
- restores the skin's protective barrier.
How to use:
After cleaning the ears, apply every 48 hours:
- 1 pump - for cats
- 2 pumps - small and medium-sized dogs
- 3 pumps - large-sized dogs
Gently massage the base of the outer ear to allow proper distribution of the product. Both the interval and the applied dose can be modified according to the veterinarian's recommendation.
Ingredients: AMP2041 (peptides), Chlorhexidine digluconate max 0.07%, TRIS-EDTA, Vitamin PP, Zinc PCA, Glycerophosphoinositol (lysine salts), Cellulose, Polyvinylpyrrolidone, Purified water.
Warning: In case of contact with eyes, rinse with water for several minutes.
Keep out of reach of children.
For topical use.
For veterinary use.
Liquid formula against excessive shedding!
Guaranteed effect in 3-6 weeks!
Norwegian anchovy oil
Norwegian sardine oil
Zinc
Biotin
Linseed oil
Wheat germ oil
Vitamins: A, E, D, B6
Add to food, 1 teaspoon/day
Tasty (chicken flavor) and easy to administer
The ideal Omega-3/Omega-6 ratio, antioxidants, vitamins and minerals to combat excessive shedding.
Strengthens optimal skin and coat health.
For maximum and rapid efficiency, it is recommended to use SHED-X shampoos concomitantly.
HISTAMINE CONTROL NUTRITIONAL COFACTORS that support histamine neutralization. Allergic reactions occur as an exaggerated response of the body to the absorption of a foreign substance (allergen). At that moment, histamine is released, present in mast cells, cells concentrated in the skin and respiratory tract.
Histamine is the chemical mediator that appears following allergenic reactions, and consequently the main cause of symptoms caused by allergies. Antihistamines are substances that block the action of histamine. The most commonly used are corticosteroids, which, in addition to their anti-inflammatory action, also have an immunosuppressive role.
HISTAMINE CONTROL has been formulated based on natural substances with nutritional properties that can be used by the body to combat histamine. It can be recommended as an alternative or adjuvant in corticosteroid treatment. It regulates the immune system by reducing the body's immune reactions to allergenic factors.
1. INGREDIENTS: Each tablet contains: Quercetin 125 mg, Bromelain 50 mg, MSM 150 mg, Grape seed extract 75 mg, Dimethylglycine 50 mg, Ascorbic acid 125 mg, Zinc lactate 50 mg, Magnesium citrate 50 mg.
2. INDICATIONS: Neutralizes histamine production in allergic processes: food allergies, asthma, allergic rhinitis, eczema, and urticaria.
3. PROPERTIES: Quercetin - a bioflavonoid with antioxidant action. It compensates for the modulating activity of vitamin C in inflammatory processes. It inhibits both the enzymes involved in the appearance of prostaglandins and leukotrienes - the main mediators of inflammation, and the production of histamine by stabilizing the level of basophils and mast cells. It acts directly on the intestines to reduce allergenic symptoms caused by food. Researchers in Brazil and Korea have successfully protected animals from food allergies by administering Quercetin orally or by inhalation. Bromelain - a proteolytic enzyme extracted from the pineapple stem, primarily helps improve protein digestion. It activates anti-inflammatory prostaglandins and thus has a beneficial action on inflammation, edema, and pain caused by fibrinolysis. It has anti-inflammatory effects even in cases of ulcerative colitis. Many scientific studies have been published in the last 10 years, demonstrating that the anti-inflammatory and analgesic action of bromelain is as effective or more effective than that of synthetic anti-inflammatory drugs. MSM (methylsulfonylmethane) - a natural source of sulfur, acts as an adjuvant in treating allergies due to the fact that it blocks the attachment of histamine to sensitive mucosal tissues. Thus, it reduces the associated symptoms of respiratory allergies and successfully combats itching in cases of allergic dermatitis. Grape seed extract - has a special effect in combating inflammation that appears as an allergic response. Proanthocyanidins have increased antioxidant power against free radicals produced in lipid peroxidation processes. Dimethylglycine - a nutrient derived from glycine, which has regulatory properties on the immune system. It facilitates the absorption of oxygen into cells, neutralizing complex free radicals. Ascorbic acid - Vitamin C - a very powerful antioxidant against free radicals involved in inflammatory processes. It has an antihistamine effect and intervenes in the correction and proper functioning of the immune system. Zinc - a cofactor of superoxide dismutase, a reference antioxidant in the body, is involved in the formation of over 100 enzymatic processes. Zinc ions stabilize the plasma membrane of mast cells, reducing and modulating the release of histamine. Magnesium - magnesium deficiency studied in experimental animals (mice) is manifested by hyperemia, increased IgE, neutrophilia, or eosinophilia. It increases the level of pro-inflammatory cytokines, mast cell degranulation, histanemia, and splenomegaly.
4. ADMINISTRATION METHOD: Target animals: Dogs, cats. Administer orally, if possible, without mixing with food. 1 tablet / 10 kg body weight / twice a day. Small cats and dogs ½ tablet / twice a day.
5. PACKAGING: Plastic bottle - 60 tablets
6. STORAGE: Store in conditions protected from moisture and direct sunlight, at room temperature.
7. CAUTION! For veterinary use only! Keep out of reach of children! Please contact your veterinarian before recommending or using this product, as changes in dosage or method of use may occur depending on individual symptoms.


