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2466 products
Soft and palatable chewable tablets, providing complex osteoarticular support for dogs.
ULTRA ingredients for maintaining joint flexibility.
Ingredients/tablet:
Glucosamine HCl (marine source) 250mg, MSM 200mg, Creatine 250mg, EPA 15 mg, DHA 10 mg, Vit. C 10 mg. Vit. E 50 IU, Hyaluronic Acid 5 mg, AyFlex® 42mg, UC II® 10mg (Total Collagen 2.5mg), Grape Seed Extract 25 mg, Boswellia Serrata 20mg, Zinc 15mg, Alpha Lipoic Acid 10mg, L-Glutathione 5mg, Manganese 2mg, Selenium 70 mcg.
Administration:
Dogs 2.5kg- 13 kg BW - 0.5 tab/ day
Dogs 14 kg- 27 kg BW - 1 tab/ day
Dogs 28 kg- 45 kg BW - 2 tabs/ day
Dogs over 45 kg BW - 2.5 tabs/ day
INTEGRA PROTECT Renal was specially created for dogs with chronic kidney failure. To support kidney function, the significantly reduced protein content means there are fewer protein breakdown products that need to be excreted. The reduced phosphorus content also delays the deterioration of kidney function.
- Reduced phosphorus content
- Grain-free, soy-free
- 100% fresh meat ingredients
Ingredients: Meat and animal derivatives (15% turkey, 8% lamb), milk and dairy products (2% cream, 1% yogurt), cereals, minerals.
- Protein: 6.6%
- Fat: 14%
- Crude fiber: 3%
- Crude ash: 5.6%
- Calcium: 0.21%
- Phosphorus: 0.15%
Feeding recommendations:
Dog's weight g / day
3-7 kg 330-450 g
8-12 kg 150-300 g
Metabolizable energy 0.66 MJ / 100g
Vom Feinsten Adult offers you the promise of delicious, healthy, and balanced nutrition of the highest quality for adult dogs aged 1 to 6 years. The careful selection and quality of meaty ingredients guarantee a unique culinary delight. This fine pâté provides all the essential nutrients an adult dog needs.
Composition: 63% meat and animal derivatives (pork, beef, poultry, 14% venison), minerals.
Ingredient Analysis:
| Proteins | 10.5 % |
| Fats | 4.5 % |
| Fibers | 0.4 % |
| Ash | 2.5 % |
| Moisture | 81 %. |
Feeding recommendation:
| Weight | g per day |
|---|---|
| 2 - 3 kg | 220 - 300 g |
| 5 - 10 kg | 440 - 750 g |
Metabolizable energy per 100g in MJ: 0.36
Nutritional additives per kilogram
- 150 IU 3a671
- 1 mg 3b406
- 26 mg 3b605
- 1.7 mg 3b503
- 0.4 mg 3b202
Other information:
- Contains drinking water. Drinking water is not a feed material and therefore cannot be listed in the declaration.
- Minerals are essential inorganic nutrients. A distinction is made between bulk and trace elements. Bulk elements occur in quantities over 50 mg / kg body weight; trace elements are below this level.
With this attractive collar, your dog will be perfectly equipped for walks. The collar is made of naturally dyed black leather and has a very solid and durable buckle.
Leather collar for very large dogs – Made of genuine leather with metal accessories.
Intended exclusively for pets.
Care: wipe the leather with a dry cloth and apply a special leather cream.
Features and benefits:
- It is made of a durable material.
- Easy and quick to put on the dog.
- For very large dogs
- Dimensions: 70cm x 4cm
Reflex Junior Small Breed with Salmon – Hypoallergenic 3 kg
Super-premium dry food for small breed puppies
Reflex Junior with Salmon is a hypoallergenic dry food, specially formulated for growing small breed puppies. It contains high-quality salmon, an excellent source of easily digestible protein and Omega 3 fatty acids, which support brain development, skin health, and coat shine.
Thanks to its hypoallergenic formula, free of wheat or high-allergen ingredients, it is ideal for sensitive puppies or those with food intolerances. The balanced content of vitamins, minerals, and natural antioxidants supports the harmonious development of the immune, skeletal, and digestive systems.
Key Benefits:
- Hypoallergenic salmon – ideal for sensitive stomachs
- Supports healthy growth of small breed puppies
- Omega 3 and 6 for healthy skin and a shiny coat
- Enriched with essential vitamins and minerals for development
Net weight: 3 kg
Recommended for: Small breed junior puppies (up to 12 months old)
COMPOSITION:
- Processed salmon protein (20%)
- Processed animal protein
- Corn, Wheat, Chicken fat
- Hydrolyzed animal protein, Salmon oil, Rice, Fish flavor
- Whey powder, Fiber concentrate, Vitamins and minerals, MOS, XOS
- Brewer's yeast, L-Carnitine, Flaxseed, Salt, Yucca Schidigera
- Preservatives and antioxidants (E320 & E321)
Analytical components:
- Crude protein: 30%
- Crude fat: 18%
- Crude fiber: 2.5%
- Crude ash: 7.5%
Vitamins:
- A: 18,000 IU/kg, D3: 1,500 IU/kg, E: 200 mg/kg, C: 200 mg/kg
- K3: 0.25 mg/kg, B1: 3 mg/kg, B2: 7.5 mg/kg, B3: 25 mg/kg
- B6: 2 mg/kg, B12: 0.05 mg/kg, B7: 0.2 mg/kg, B9: 0.5 mg/kg
- Choline: 2,500 mg/kg, Calcium pantothenate: 20 mg/kg
Minerals:
- Iron: 150 mg/kg, Iodine: 1.5 mg/kg, Copper: 15 mg/kg
- Manganese: 70 mg/kg, Zinc: 180 mg/kg, Selenium: 0.3 mg/kg
COMPOSITION: meat and animal by-products (duck meat, chicken meat, beef, pork, beef and pork offal).
Guaranteed Analysis: crude protein 16%, crude fat 11%, crude fiber 0.5%, crude ash 2.5%, moisture 70%, naturally high content of vitamins (A, E, D), amino acids (lysine, methionine, cysteine) and minerals.
A combination of nutrients that ensures an optimal diet.
Serve at room temperature.
Store in a cool place after opening.
The product does not contain: soy, flavorings, preservatives and colorants.
Production is under constant veterinary supervision.
Store in a cool and dry place.
Expiration date is on the packaging.
Recommended feeding portions:
dog weight – daily portion
2 kg – 60 g
2-3 kg – 120 g
3-5 kg – 240 g
5 kg – 200 g
10 kg – 400 g
20 kg – 600 g
30 kg – 800 g
CESAR has created a collection of high-quality recipes, for 100% delicious and 100% complete food, that your dog will love... making every meal a truly shared joy.
INGREDIENTS
Composition: meat and animal derivatives (45%, including 4% turkey, 4% beef), cereals, minerals, derivatives of vegetable origin, vegetable protein extracts.
ADDITIVES
Additives per Kg: Nutritional additives: vitamin D3 150 IU, calcium iodate, anhydrous 0.39mg, copper sulphate, pentahydrate 4.1mg, iron sulphate, monohydrate 10mg, manganese sulphate, monohydrate 5.6 mg, zinc sulphate, monohydrate 44.5mg.
ANALYSIS
Analytical constituents (%):
Protein 9,
Fat content 5.5,
Inorganic matter 2,
Crude fiber 0.3,
Moisture 81.
BENEFITS
1. 100% complete, delicious and healthy dog food: for 100% mealtime joy
2. CESAR Classics are those timeless and authentic dog food recipes, lovingly created by Cesar for over 25 years
3. 150g tray, with meat chunks in compact mass or jelly
4. Quality pet food, with carefully selected ingredients
5. Delicious dog food recipes, with no added sugars, no artificial colors or flavors
FEEDING GUIDE
Feeding instructions: feed daily with: 2½ cans for a 5kg dog, 3 cans for a 7kg dog
and 4 cans for a 10kg dog. It is recommended to offer your dog a mix of wet and dry food, proportionally reducing the amount offered of each type of food. Make sure the transition to a new type of food is done gradually. A bowl of fresh water should always be available. Serve at room temperature. Once opened, the product should be stored in the refrigerator.
It is a range of authentic and timeless recipes, lovingly created over 25 years.
Large and tender pieces that will transform every meal for your dog into moments of joy for him... and for you.
And because all CESAR recipes are healthy and provide 100% complete nutrition, your dog can enjoy them whenever you wish.
At 8 years old, a small dog is not yet elderly, but will start to show the first signs of aging. To keep your dog in the best possible condition for as long as possible, you need to adapt their food according to the specific symptoms of aging (slow intestinal tract, sensitive kidneys, joint pain, etc.). In addition, it is important that food for small dogs is adapted to their physiological characteristics - jaw size, bone structure, digestive system, and energy requirements. Royal Canin knows how important it is to have your four-legged companion by your side for as long as possible, which is why it has developed food adapted to these needs.
Royal Canin Mini Adult dry food is formulated according to these special characteristics of adult small breed dogs (1 - 10 kg) from 8 years old and up.
Ingredients: corn, rice, poultry protein (dried), animal fat, corn flour, corn gluten, vegetable protein isolate*, animal protein (hydrolyzed), beet pulp, soybean oil, minerals, fish oil, fructo-oligosaccharides yeast, borage oil, marigold flower meal (source of lutein).
* L.I.P.: proteins specially selected for their very high digestibility and high biological value.
Additives
-
Nutritional additives: vitamin A (22,000 IU/kg), vitamin D3 (1,000 IU/kg), E1
(44 mg/kg), E2 (4.4 mg/kg), E4 (13 mg/kg), E5 (57 mg/kg), E6 (140 mg/kg), E8 (0.087 mg/kg), L-carnitine (50 mg/kg).
- Sensory additives: Tea extract (source of polyphenols) (150 mg). Preservatives, antioxidants.
Analysis
| protein | 27.0 % |
| fat | 16.0 % |
| fiber | 1.5 % |
| ash | 4.9 % |
Feeding recommendation
| Dog's weight | Low activity | Normal activity | High activity |
| 2 kg | 40 | 47 | 53 |
| 3 kg | 54 | 63 | 72 |
| 4 kg | 68 | 78 | 89 |
| 5 kg | 80 | 93 | 105 |
| 6 kg | 92 | 106 | 121 |
| 7 kg | 103 | 119 | 135 |
| 8 kg | 114 | 132 | 150 |
| 9 kg | 124 | 144 | 163 |
| 10 kg | 134 | 156 | 177 |
GranCarno® Original Adult provides delicious, healthy and balanced nutrition at the highest level for adult dogs aged 1 to 6 years. The fresh, meat-based ingredients guarantee the incomparable taste that dogs appreciate so much. GranCarno Original Adult provides all the essential nutrients an adult dog needs.
- No artificial colors or preservatives
- 100% fresh meat ingredients
- No soy, no grains
Ingredients: 58% pork (heart, liver, lung, meat), 20% poultry hearts, sodium chloride. Protein 11.5%, fat 4%, crude fiber 0.3%, crude ash 2.2%, moisture 80%.
- Protein: 11%
- Fat: 8.5%
- Crude fiber 0.5%
- Crude ash: 1.8%
- Moisture: 78%
Feeding recommendations:
Dog's weight low activity normal activity
3 kg 180 g 210 g
5 kg 265 g 300 g
10 kg 450 g 515 g
15 kg 610 g 700 g
20 kg 760 g 870 g
25 kg 895 g 1030 g
30 kg 1025 g 1180 g
40 kg 1275 g 1465 g
60 kg 1725 g 1985 g
Metabolizable energy 0.46 MJ / 100g
INTEGRA PROTECT Sensitive has been specially developed for dogs with food intolerances, whose main symptoms are itching and diarrhea. Strictly limiting the use of animal and vegetable protein sources can help. INTEGRA PROTECT Sensitive contains only two protein sources: lamb and amaranth.
- Only one animal protein source: lamb
- Prevents the formation of kidney stones
- Only one vegetable protein source: amaranth
Ingredients: Lamb (58%), amaranth (2.5%), calcium carbonate, rapeseed oil (0.4%), sodium chloride.
- Protein: 9%
- Fat: 8%
- Crude fiber: 0.5%
- Crude ash: 1.8%
- Moisture: 78%
Feeding recommendations:
Dog weight g / day
3-7 years 200-400 g
12-17 years 600-800g
Metabolizable energy 0.47 MJ / 100g
Vom Feinsten Adult offers you the promise of delicious, healthy, and balanced nutrition of the highest quality for adult dogs aged 1 to 6 years. The careful selection and quality of meaty ingredients guarantee a unique culinary delight. This fine pâté provides all the essential nutrients an adult dog needs.
- No artificial colors or preservatives
- Carefully selected meat ingredients
- No soy, no sugar
Ingredients: 59% meat and animal derivatives (poultry, pork, beef, 8% lamb), cereals (4% wheat), minerals.
- Protein: 10.5%
- Fat: 4.5%
- Crude fiber: 0.4%
- Crude ash: 2.5%
- Moisture: 81%
Feeding recommendations:
Dog weight low activity high activity
3 kg 260 g 300 g
5 kg 380 g 440 g
10 kg 640 g 740 g
Metabolizable energy 0.36 MJ / 100g
Vom Feinsten Junior offers the promise of delicious, healthy, and balanced nutrition at the highest quality level for your dog's growth in the first year of life.
- No artificial colors and preservatives
- Carefully selected meat ingredients
- No soy, no sugar
Ingredients: 63% meat and animal derivatives (20% poultry, pork, beef, 8% turkey heart), minerals.
- Protein: 11%
- Fat: 7%
- Crude fiber 0.4%
- Crude ash: 1%
- Moisture: 80%
Feeding recommendations:
Age (Weeks) Weight Food quantity
10 0.9 kg 165 g
20 1.8 kg 200 g
> 30 2.55 kg 235 g
Metabolizable energy 0.43 MJ / 100g
GranCarno® Original Adult provides delicious, healthy, and balanced nutrition at the highest level for adult dogs aged 1 to 6 years. The fresh, meat-based ingredients guarantee the incomparable taste that dogs love so much. GranCarno Original Adult provides all the essential nutrients an adult dog needs.
- No artificial colors or preservatives
- 100% fresh meat ingredients
- No soy, no grains
Ingredients: Beef 38% (lung, liver, meat, heart, kidney, udder), 30% chicken (meat, heart, stomach, liver, neck), calcium carbonate.
- Protein: 11%
- Fat: 8.5%
- Crude fiber: 0.5%
- Crude ash: 1.8%
- Moisture: 77%
Feeding recommendations:
Dog's weight low activity normal activity
3 kg 180 g 210 g
5 kg 265 g 300 g
10 kg 450 g 515 g
15 kg 610 g 700 g
20 kg 760 g 870 g
25 kg 895 g 1030 g
30 kg 1025 g 1180 g
40 kg 1275 g 1465 g
60 kg 1725 g 1985 g
Metabolizable energy 0.46 MJ / 100g
GranCarno Junior offers delicious, healthy, and balanced nutrition at the highest level for growing puppies in their first year. Selected fresh, meaty ingredients guarantee the incomparable taste that dogs appreciate so much. GranCarno Junior - with its smaller meaty pieces, suitable for puppies - is specially adapted to the nutritional needs of growing puppies.
- No artificial colors or preservatives
- 100% fresh meat ingredients
- No soy, no grains
Ingredients: 51% beef (meat, lungs, liver, udder, kidneys), 17% heart, calcium carbonate.
- Protein: 11%
- Fat: 8.5%
- Crude fiber: 0.5%
- Crude ash: 1.8%
- Moisture: 78%
Metabolizable energy 0.46 MJ / 100g
GranCarno Junior offers delicious, healthy, and balanced nutrition of the highest quality for growing puppies in their first year. Selected fresh and meaty ingredients guarantee the incomparable taste that dogs love so much. GranCarno Junior - with its smaller, puppy-friendly meaty chunks - is specially adapted to the nutritional needs of growing puppies.
- No artificial colors or preservatives
- 100% fresh meat ingredients
- No soy, no grains
Ingredients: 40% beef (lungs, meat, heart, liver, kidney, udder), 28% chicken (meat, liver, stomach, neck), calcium carbonate, 0.2% salmon oil.
- Protein: 10.5%
- Fat: 8%
- Crude fiber: 0.4%
- Crude ash: 2%
- Moisture: 77.5%
Metabolizable energy: 0.49 MJ / 100g
Bitches and puppies transitioning to solid food during weaning need a diet adapted to their individual needs. Royal Canin Mini Starter Mother & Babydog has been developed for this purpose. This recipe is suitable for adult small breed bitches weighing up to 10 kg and puppies aged 3 to 8 weeks. The food is specially adapted to the increased energy requirements of small breed bitches in late gestation and during lactation. It has been created to support the normal development of puppies.
Royal Canin Mini Starter Mother & Babydog contains a complex of vitamins C and E to support the optimal development of the immune system. Thanks to the combination of beneficial prebiotics and easily digestible proteins, the food aids normal digestion. In addition, the food is enriched with Omega-3 fatty acids, which support the normal brain development of puppies.
Royal Canin Mini Breed Starter Mother & Babydog Dry Food, description:
- Complete food for pregnant small breed bitches (up to 10 kg) and puppies (aged 3-8 weeks)
- Supports the immune system: through a customized nutrient complex including vitamins C & E
- Gut microbiome balance: with easily digestible proteins and prebiotics (MOS)
- Omega-3 fatty acids: support normal brain development and learning
- Adapted energy needs: for small breed mother dogs and puppies
- Suitable for weaning: rehydratable kibble to prepare a gruel for puppies
The kibble in Royal Canin Mini Starter Mother & Babydog food is easy to rehydrate with water, forming an appetizing gruel texture, ideal for weaning puppies. This facilitates the transition from mother's milk to solid food.
Ingredients
Dehydrated poultry protein, rice, animal fat, wheat gluten*, maize, dried beet pulp, hydrolyzed animal protein, minerals, soya oil, fish oil, fructooligosaccharides, hydrolyzed yeast (source of mannan-oligosaccharides and beta-glucans) (0.30%), Schizochytrium sp. algal oil (source of DHA), butyrate, marigold meal.
*L.I.P.: protein selected for its very high digestibility.
Additives
Nutritional additives:
vitamin A (18,500 IU/kg), vitamin D3 (1,200 IU/kg), vitamin E (500 mg/kg), vitamin C (400 mg/kg), iron (40 mg/kg), iodine (4 mg/kg), copper (12 mg/kg), manganese (52 mg/kg), zinc (131 mg/kg), selenium (0.07 mg/kg).
Technological additives:
clinoptilolite of sedimentary origin (10 g/kg), preservatives, antioxidants.
Analysis
| protein | 30.0 % |
| fat | 22.0 % |
| fiber | 1.3 % |
| ash | 8.5 % |
| Omega-3 fatty acids | 0.2 % |
| metabolizable energy | 4209.0 kcal/kg |
Feeding recommendation
Royal Canin Mini Breed Starter Mother & Babydog is a complete food for puppies and pregnant bitches.
| Dog weight | For puppies | For pregnant bitches | ||||
| 0 - 3 weeks | 3 - 6 weeks | 6 - 8 weeks | 6 weeks | 8 weeks | during lactation | |
| 1 kg | Babydog milk | 23 g | 45 g | 29 g | 34 g | ad libitum |
| 3 kg | Babydog milk | 23 g | 45 g | 66 g | 77 g | ad libitum |
| 5 kg | Babydog milk | 33 g | 88 g | 96 g | 114 g | ad libitum |
| 7 kg | Babydog milk | 43 g | 133 g | 124 g | 146 g | ad libitum |
| 10 kg | Babydog milk | 43 g | 133 g | 162 g | 191 g | ad libitum |
Oncovet I is a food supplement in tablet form, for dogs and cats of all ages. The product is indicated for oncological conditions in pets with nutritional deficiencies that are difficult to compensate. In these cases, the normal functions of the body are severely compromised, requiring an antioxidant and nutritional adjuvant for the elimination of tumor cells.
It is also beneficial during chemotherapy and radiotherapy, as well as before and after surgical operations. Thanks to the included amino acids (L-glutamine), the formula alleviates the side effects of these treatments, strengthens the immune system and reduces the risk of recurrence.
Silymarin, pomegranate extract, green tea and grape seeds have a strong antioxidant and immunomodulatory effect, fighting against free radicals and protecting cells from further damage. It is recommended to combine with Oncovet II.
Composition: Glutamic acid, silymarin, pomegranate, green tea, turmeric, grape seeds, L-selenomethionine, excipients.
Administer 1 tablet/10 kg body weight, twice a day.
Absorbent pad 10 pcs/pack
The box contains 12 packs
Size: 60x90cm
Prevents leaks and unpleasant odors.
Features
Five-layer construction: designed for extra absorbency and extended use.
Built-in odor control: specially designed to neutralize harsh urine odors.
Quick-drying: made with advanced technology that locks in moisture for quick drying.
Attractive to puppies: speeds up training time by encouraging instinctive marking.
Antimicrobial protection: protects against odors from microorganisms.
Instructions
Unfold and place the pet training pad on the floor, plastic side down and tissue side up.
Always keep the pad in an area accessible to your pet, but away from their bed and food.
Place your pet on the pad so they can smell its special scent. If they don't relieve themselves immediately, bring them back several times until they are successful.
When they relieve themselves on the pad, reward them with a treat or enthusiastic praise.
To train your pet to eliminate outside, gradually move the pad closer to the door and eventually outside.
Training pads also have other uses...
Litter box mats / dog crate liners / for muddy paws and messy spills / car mats / travel and much more...
Brit Care Senior, Lamb and Rice 12 kg is a super-premium dry food for senior dogs of all sizes.
The formula contains fructo-oligosaccharides that nourish beneficial microbial flora in the intestines, while mannan-oligosaccharides maintain intestinal health by reducing pathogenic microflora. The balanced intake of Omega-3 and Omega-6 fatty acids and chelated copper protects the vascular system from the harmful action of cholesterol. Brit Care Senior All Breed Lamb and Rice is enriched with organic selenium and Vitamin E, which help slow down cellular aging by protecting the body from the action of free radicals. The combination of vitamins and choline chloride ensures optimal functioning of the nervous system.
Ingredients: lamb meal, rice, chicken fat (preserved with tocopherols), salmon oil, natural flavors, brewer's yeast, dried apples, minerals, hydrolyzed crustacean shells (source of glucosamine – 260 mg/kg), cartilage extract (source of chondroitin – 160 mg/kg), mannan-oligosaccharides (150 mg/kg), fructo-oligosaccharides (100 mg/kg), yucca schidigera extract (80 mg/kg).
| Average Analysis | Nutritional Additives | |||
| Proteins | 25 % | Vitamin A | 20000 IU | |
| Fats | 12 % | Vitamin D3 | 1500 IU | |
| Moisture | 10 % | Vitamin E (alpha-tocopherols) | 7500 mg | |
| Ash | 6 5 % | Zinc | 70 mg | |
| Fibers | 4 % | Iron | 80 mg | |
| Calcium | 1 5 % | Manganese | 36 mg | |
| Phosphorus | 1 % | Iodine | 0 65 mg | |
| Metabolizable energy | 3842 kcal/kg | Copper | 20 mg | |
| Selenium | 0 2 mg | |||
| Biotin | 0 6 mg | |||
| Choline chloride | 600 mg | |||
| Folic acid | 0 5 mg | |||
| Calcium pantothenate | 10 mg | |||
| Vitamin B1 | 4 mg | |||
| Vitamin B12 | 0 04 mg | |||
| Vitamin B2 | 5 mg | |||
| Vitamin B6 | 4 mg | |||
The food quantities in the feeding guide are indicative and should be adjusted according to the dog's particular needs (age, activity level, weather conditions). The dog's weight should be carefully monitored, and periodic visits to the vet are necessary. The dog must always have fresh water available.
Feeding Guide:
| Weight (kg) | 2 | 10 | 15 | 20 | 25 | 30 | 40 | 50 | 60 | 70 | 80 | 90 |
| Daily food quantity (g) | 70 | 115 | 150 | 180 | 220 | 260 | 320 | 380 | 430 | 480 | 530 | 580 |
Medium-sized dogs are often more robust and agile than other dogs. They have a wide range of activities, they can be quiet family dogs or high-performance dogs. Family dogs tend to gain weight and need a carefully measured amount of food, while performance dogs (e.g., hunting or racing dogs) have high energy requirements. Dogs that rummage through bushes, play in the water, etc., need extra protection for their skin and coat.
Medium-sized dogs that spend a lot of time outdoors are more prone to infections and need a strong immune system.
Royal Canin Medium Puppy dry food is designed according to the special characteristics of growing medium-sized dogs (11 - 25 kg) over 2 months old.
Ingredients: poultry protein (dried), animal fats, maize, vegetable protein isolate*, dried beet pulp, whole wheat flour, rice, animal protein (hydrolysed), wheat, maize flour, fish oil, yeast, soya oil, minerals, fructo-oligo-saccharides (0.34 %), yeast hydrolysate (source of mannan-oligosaccharides), yeast extract (source of beta-glucans), marigold meal (source of lutein).
* L.I.P.: specially selected, easily digestible proteins with high biological value.
Additives
-
Nutritional additives:
vitamin A (16,000 IU/kg), vitamin D3 (1,000 IU/kg), vitamin E (520 mg/kg), E1(45 mg/kg), E2 (4.5 mg/kg), E4 (14 mg/kg), E5 (59 mg/kg), E6 (123 mg/kg), E8 (0.08 mg/kg). -
Technological additives:
Clinoptilolite of sedimentary origin (10 g/kg). -
Sensory additives:
Yucca extract (125 mg/kg). Preservatives, antioxidants.
Analysis
| protein | 32.0 % |
| fat | 20.0 % |
| fibre | 1.6 % |
| ash | 7.9 % |
Feeding recommendation
| Age in months | 11 kg | 14 kg | 18 kg | 22 kg | 25 kg |
| 2 months | 155 g | 184 g | 217 g | 237 g | 244 g |
| 3 months | 182 g | 216 g | 259 g | 288 g | 300 g |
| 4 months | 194 g | 232 g | 279 g | 311 g | 325 g |
| 5 months | 197 g | 236 g | 285 g | 324 g | 347 g |
| 6 months | 197 g | 236 g | 285 g | 332 g | 366 g |
| 8 months | 159 g | 204 g | 247 g | 298 g | 330 g |
| 10 months | 141 g | 169 g | 205 g | 239 g | 264 g |
| 12 months | Medium Adult | Medium Adult | 202 g | 235 g | 261 g |
| 13 months | Medium Adult | Medium Adult | Medium Adult | Medium Adult | 259 |
QUALITATIVE AND QUANTITATIVE COMPOSITION
Each chewable tablet contains:
Active substances:
|
NEXGARD SPECTRA |
Afoxolaner (mg) |
Milbemycin oxime (mg) |
| chewable tablets for dogs 7.5-15 kg | 150.00 | 30.00 |
PHARMACEUTICAL FORM
Chewable tablets.
Mottled red to reddish-brown tablets, round (tablets for
dogs 2-3.5 kg) or rectangular (tablets for dogs > 3.5-7.5 kg, tablets for dogs > 7.5-15 kg, tablets for dogs > 15-30 kg and tablets for dogs > 30-60 kg).
CLINICAL PARTICULARS
Target species: Dogs
Indications for use, specifying the target species
For the treatment of flea and tick infestations in dogs when concurrent prevention of heartworm disease and/or treatment of gastrointestinal nematode infestations is indicated.
Treatment of flea infestations (Ctenocephalides felis and C. canis) in dogs for 5 weeks. Treatment of tick infestations (Dermacentor reticulatus, Ixodes ricinus, Rhipicephalus sanguineus) in dogs for 4 weeks.
Fleas and ticks must attach to the host and commence feeding to be exposed to the active substance.
Treatment of adult gastrointestinal nematode infestations of the following species: roundworms (Toxocara canis and Toxocara leonina), hookworms (Ancyclostoma caninum and Ancyclostoma braziliense) and whipworms (Trichuris vulpis).
Prevention of heartworm disease (Dirofilaria immitis larval stage) if administered monthly.
Contraindications: Do not use in case of hypersensitivity to the active substances or to any of the excipients.
Special warnings for each target species
Parasites need to start feeding on the host to be exposed to afoxolaner; therefore, the risk of transmission of infectious diseases cannot be excluded.
Resistance of parasites to any particular class of antiparasitic medicinal products may develop following frequent, repeated use of a compound of that class. Therefore, the use of this product should be based on an individual case assessment and local epidemiological information about the current susceptibility of the target species to limit the possibility of future selection of resistance.
Maintaining the efficacy of macrocyclic lactones is essential for the control of Dirofilaria immitis. To minimise the risk of resistance selection, it is recommended to test dogs for both circulating antigens and blood microfilariae at the start of each preventative treatment period.
Only negative animals should be treated.
Special precautions for use
Special precautions for use in animals
In the absence of available data, treatment of puppies younger than 8 weeks and/or dogs weighing less than 2 kg should only be carried out based on a risk/benefit assessment by the veterinarian.
Dogs living in heartworm endemic areas should be tested for adult heartworm infestation before administration of NEXGARD SPECTRA. Infested dogs should be treated with an adulticide at the discretion of the veterinarian to eliminate adult heartworms. NEXGARD SPECTRA is not indicated for the elimination of microfilariae.
The recommended dose should be strictly followed in Collie breed dogs or other related breeds.
Special precautions to be taken by the person administering the veterinary medicinal product to animals
- This product, if ingested, can cause gastrointestinal disturbances.
- Keep the tablets in the blister and the blister in the carton until use.
- In case of accidental ingestion, especially by children, seek medical advice immediately and show the product label to the physician.
- Wash hands after use.
Adverse reactions (frequency and seriousness)
In clinical studies, no serious adverse reactions attributable to the combination of afoxolaner with milbemycin oxime were observed. Less common reactions such as vomiting, diarrhoea, lethargy, anorexia and pruritus have been observed. These reactions generally resolved spontaneously and were of short duration.
The frequency of adverse reactions is defined using the following convention:
- Very common (more than 1 in 10 animals displaying adverse reactions during the course of one treatment)
- Common (more than 1 but less than 10 animals in 100 animals)
- Uncommon (more than 1 but less than 10 animals in 1,000 animals)
- Rare (more than 1 but less than 10 animals in 10,000 animals)
- Very rare (less than 1 animal in 10,000 animals, including isolated reports).
Use during pregnancy, lactation or lay
Laboratory studies in rats and rabbits have not shown any teratogenic effects or any negative effects on the reproductive capacity of males and females. The safety of the veterinary medicinal product has not been established during pregnancy and lactation or in breeding dogs. Use only according to the benefit-risk assessment by the veterinarian.
Interactions with other medicinal products and other forms of interaction
Milbemycin oxime is a substrate of P-glycoprotein (P-gp), and thus may interact with other P-gp substrates (e.g., digoxin, doxorubicin) or other macrocyclic lactones. Therefore, concomitant treatment with other P-gp substrates may lead to increased toxicity.
Amounts to be administered and administration route
For oral administration.
Dosage:
The product should be administered at a dose of 2.50-5.36 mg/kg afoxolaner and 0.50-1.07 mg/kg milbemycin oxime body weight according to the following table:
| Dog weight (kg) | Concentration and number of chewable tablets to be administered | ||||
|
NEXGARD SPECTRA 9 mg/ 2 mg |
NEXGARD SPECTRA 19 mg/ 4 mg |
NEXGARD SPECTRA 38 mg/ 8 mg |
NEXGARD SPECTRA 75 mg/ 15 mg |
NEXGARD SPECTRA 150 mg/ 30 mg |
|
|
2-3.5 |
1 |
|
|
|
|
|
>3.5-7.5 |
|
1 |
|
|
|
|
>7.5-15 |
|
|
1 |
|
|
|
>15-30 |
|
|
|
1 |
|
|
>30-60 |
|
|
|
|
1 |
For dogs over 60 kg body weight, the appropriate combination of chewable tablets should be used.
Method of administration:
The tablets are chewable and palatable to most dogs. If the dog does not accept the tablets directly, they can be administered with food.
Treatment regimen:
The treatment regimen should be based on the veterinary diagnosis and local epidemiological situation.
NEXGARD SPECTRA can be used as seasonal preventive treatment against fleas and ticks (replacing treatment with a monovalent product acting only against fleas and ticks) in dogs concurrently infested with gastrointestinal nematodes. A single treatment is effective against gastrointestinal nematodes. After treating nematode infestations, treatment against flea and tick infestations can be continued by applying the monovalent product.
Disease: Heartworm disease:
NEXGARD SPECTRA kills Dirofilaria immitis larvae for one month after their transmission by mosquitoes, so the product should be administered at regular monthly intervals throughout the vector season, starting the month after the first exposure to mosquitoes. Treatment should continue until the month following the last exposure to mosquitoes. To establish a treatment routine, it is recommended to administer the treatment on the same day of the month.
If replacing another heartworm prevention product, the first treatment with NEXGARD SPECTRA should begin on the day the previous medication was due.
Dogs living in or travelling to a heartworm endemic region may be infested with adult heartworms. No therapeutic effect against adult Dirofilaria immitis has been established. Therefore, it is recommended that all dogs aged 8 months or older, living in heartworm endemic areas, be tested for adult heartworm infestation before being treated with a heartworm prevention product.
Overdose (symptoms, emergency procedures, antidotes), if applicable
No adverse reactions were observed in healthy puppies over 8 weeks of age after 6 treatments with 5 times the maximum dose.
Withdrawal period: Not applicable.
PHARMACOLOGICAL PROPERTIES
Pharmacotherapeutic group: antiparasitic products, endectocides, milbemycin combinations.
Veterinary ATC code: QP54AB51
Pharmacodynamic properties
Afoxolaner:
Afoxolaner is an insecticide and acaricide belonging to the isoxazoline family.
Afoxolaner acts by interacting with chloride ion channels, primarily those with a binding site for the gamma-aminobutyric acid (GABA) neurotransmitter, thereby blocking pre- and post-synaptic chloride ion transfers across the cell membrane. This results in uncontrolled activity of the central nervous system and death of insects and mites. The selective toxicity of afoxolaner between insects/mites and mammals is a consequence of the characteristic sensitivity of insect/mite GABA receptors versus those of mammals.
Afoxolaner is active against adult fleas as well as several tick species such as Rhipicephalus sanguineus, Dermacentor reticulatus and D. variabilis, Ixodes ricinus and I. scapularis, Amblyomma americanum and Haemaphysalis longicornis.
The product kills fleas before they lay eggs and thus prevents household contamination. It can be used as part of a treatment strategy for the control of flea allergy dermatitis (FAD).
Milbemycin oxime:
Milbemycin oxime is an endectocidal antiparasitic belonging to the macrocyclic lactone group. Milbemycin oxime is a mixture of milbemycin A4 and milbemycin A3 (in a ratio of 20:80 for A3:A4). It is isolated from the fermentation of Streptomyces milbemycinicus.
Milbemycin oxime acts by disrupting glutamate-activated neurotransmission in invertebrates. Milbemycin oxime increases the membrane permeability of nematodes and insects to chloride ions through glutamate-controlled chloride ion channels (linked to GABA and glycine receptors in vertebrates).
This leads to hyperpolarisation of the neuromuscular membrane and paralysis and death of the parasites.
Pharmacokinetic particulars
Afoxolaner is very rapidly absorbed systemically. The absolute bioavailability obtained was 88%. The mean maximum plasma concentration (Cmax) was 1822 ± 165 ng/ml, at 2-4 hours (Tmax) after a dose of 2.5 mg/kg afoxolaner.
The volume of distribution of Afoxolaner in tissues is 2.6 ± 0.6 l/kg and the clearance value is 5.0 ± 1.2 ml/h/kg. The half-life is approximately 2 weeks in dogs.
Milbemycin oxime plasma concentrations rise rapidly within the first 1-2 hours (Tmax) indicating rapid absorption from the tablet. The absolute bioavailability obtained was 81% for factor A3 and 65% for A4, respectively. The mean maximum plasma concentration (Cmax) after oral administration was 1.6 ± 0.4 days and 42 ± 11 ng/ml for A3, 3.3 ± 1.4 days and 246 ± 71 ng/ml for A4.
The volume of distribution of Milbemycin oxime in tissues is 2.7 ± 0.4 and 2.6 ± 0.6 l/kg for A3 and A4, respectively. Both forms have low clearance values of 75 ± 22 ml/h/kg for A3 and 41 ± 12 ml/h/kg for A4.
PHARMACEUTICAL PARTICULARS
List of excipients
- Corn starch
- Soy protein
- Braised beef flavour
- Povidone (E1201)
- Macrogol 400
- Macrogol 4000
- Macrogol 15 hydroxystearate
- Glycerol (E422)
- Medium chain triglycerides
- Citric acid monohydrate (E330)
- Butylhydroxytoluene (E321)
Incompatibilities: Not applicable.
Shelf life: Shelf life of the veterinary medicinal product as packaged for sale: 2 years
Special precautions for storage: Keep the blister in the secondary packaging to protect from light.
Nature and composition of primary packaging
This veterinary medicinal product is individually packed in thermoformed PVC blisters sealed on the back with aluminium foil (Aclar/PVC/Alu).
1 cardboard box containing one blister with 1, 3 and 6 chewable tablets.
Not all package sizes may be marketed.
Special precautions for the disposal of unused veterinary medicinal products or waste materials derived from the use of such products
Any unused veterinary medicinal product or waste materials derived from the use of such products should be disposed of in accordance with local requirements.
Vom Feinsten Adult offers you the promise of delicious, healthy, and balanced nutrition at the highest quality level for adult dogs aged 1 to 6 years. The careful selection and quality of the meaty ingredients guarantee a unique culinary delight. This fine pâté provides all the essential nutrients an adult dog needs.
- No artificial colors or preservatives
- Carefully selected meat ingredients
- No soy, no sugar
Ingredients: 54% turkey, 4% cheese, calcium, sodium chloride.
- Protein: 10.5%
- Fat: 4.5%
- Crude fiber: 0.4%
- Crude ash: 2%
- Moisture: 81%
Feeding recommendations:
Dog's weight Low activity High activity
3 kg 260 g 300 g
5 kg 380 g 440 g
10 kg 640 g 740 g
Metabolizable energy 0.36 MJ / 100g
INTEGRA PROTECT Renal was specially developed for dogs with chronic renal failure. To support kidney function, the significantly reduced protein content means there are fewer protein breakdown products that need to be excreted. The reduced phosphorus content also delays the deterioration of kidney function. This sustainably improves the dog's health and can prolong life expectancy.
MULTIFUNCTIONAL: This dietary food is grain-free, making it also suitable for dogs with grain intolerance.
Ingredients: Meat and animal derivatives (25% beef), vegetables (potatoes), derivatives of vegetable origin, oils and fats (canola oil), minerals. Protein sources: chicken, pork.
- Protein: 4%
- Fat: 11%
- Crude Fiber 0.8%
- Crude Ash: 1.5%
- Moisture: 80%
- Calcium 0.15%
- Phosphorus 0.1%
- Sodium 0.16%
- Potassium 0.26%
- Linoleic acid 2%.
Feeding recommendations:
| Dog's weight | g per day |
|---|---|
| 3 - 7 kg | 215 - 400 g |
| 12 - 17 kg | 600 - 800 g |
Metabolizable energy 0.49 MJ / 100g
INTEGRA PROTECT Intestinal has been specially developed for dogs with acute diarrhea. Highly digestible animal proteins and carbohydrates, easy on the stomach, protect the gastrointestinal tract. The increased electrolyte content compensates for losses caused by vomiting and diarrhea.
- Highly digestible, gluten-free rice
- Highly digestible turkey
- 100% fresh meat ingredients
Ingredients: Meat and animal derivatives (15% turkey, 8% lamb), milk and dairy derivatives (2% cream, 1% yogurt), cereals, minerals.
- Protein: 9%
- Fat: 5%
- Crude fiber 0.3%
- Crude ash: 2%
- Calcium: 0.27%
- Phosphorus: 0.22%
Feeding recommendations:
Dog's weight g / day
2 - 5 kg 150 - 400 g
5 - 10 kg 400 - 600 g
Metabolizable energy 0.40 MJ / 100g
Vom Feinsten Junior offers the promise of delicious, healthy, and balanced nutrition of the highest quality for a dog's growth in the first year of life. This delicious pâté is specially adapted to the nutritional requirements of junior dogs.
- No artificial colors or preservatives
- Carefully selected meat ingredients
- No soy, no sugar
Ingredients: 63% meat and animal derivatives (30% beef, pork, 10% poultry), minerals.
- Protein: 11%
- Fat: 7%
- Crude fiber: 0.4%
- Crude ash: 1%
- Moisture: 80%
Feeding recommendations:
Age (Weeks) Weight Food quantity
10 0.9 kg 165 g
20 1.8 kg 200 g
> 30 2.55 kg 235 g
Metabolizable energy 0.43 MJ / 100g
