Advantix antiparasitic pipette for dogs weighing from to

59,00 lei

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Pipetă antiparazitară Advantix pentru câini de la 4 kg până la 10 kg

59,00 lei

59,00 lei

DESCRIERE

Advantix is an external antiparasitic product containing imidacloprid and permethrin, and is highly effective in treating flea and tick infestations for one month after a single application.

Composition
Each dose (pipette) contains:

Pipette Imidacloprid Permethrin E321
Advantix spot-on solution for dogs up to 4 kg 0.4 ml 40 mg 200 mg 0.4 mg
Advantix spot-on solution for dogs from 4 kg to 10 kg 1.0 ml 100 mg 500 mg 1.0 mg
Advantix spot-on solution for dogs from 10 kg to 25 kg 2.5 ml 250 mg 1250 mg 2.5 mg
Advantix spot-on solution for dogs over 25 kg 4.0 ml 400 mg 2000 mg 4.0 mg

Excipients: Butylated hydroxytoluene 1.0 mg/ml (E321, as an antioxidant):

Indications
For the treatment and prevention of flea infestation (Ctenocephalides canis, Ctenocephalides felis).
Fleas on dogs are killed within one day of treatment. One treatment prevents future flea infestations for four weeks. The product
can be used as part of a treatment strategy against flea allergy dermatitis (FAD).
The product exhibits acaricidal and repellent activity for up to four weeks (Rhipicephalus sanguineus, Ixodes
ricinus) or three weeks (Dermacentor reticulatus) against tick infestations.
Ticks already present on the dog may not be killed within two days after treatment and may remain attached and visible. Therefore,
it is recommended to remove ticks present on the dog at the time of treatment to prevent them from attacking and feeding on blood.
One treatment provides repellent (anti-feeding) action against sandflies for two weeks (Phlebotomus papatasi) or three
weeks (Phlebotomus perniciosus), against mosquitoes for two (Aedes aegypti) and four (Culex pipiens) weeks, and against stable flies
(Stomoxys calcitrans) for four weeks.
Sandflies Phlebotomus perniciosus 3 weeks
Phlebotomus papatasi 2 weeks
Mosquitoes Aedes aegypti 2 weeks
Culex pipiens 4 weeks
Stable fly Stomoxys calcitrans 4 weeks

Contraindications
In the absence of available data, the product should not be used in puppies younger than 7 weeks.
Do not use in cases of known hypersensitivity to the active substances.
Do not use in cats.

Adverse reactions
Transient skin sensitivity (with increased itching, alopecia and erythema at the application site) or apathy may rarely occur.
Poisoning in dogs after accidental ingestion may occur in rare cases. In these cases, neurological signs such as
tremors and apathy may also appear. Symptomatic treatment should be applied under veterinary supervision. There is no specific antidote.
If you notice any serious reactions or other effects not mentioned in this leaflet, please inform your veterinarian.

Target species
Dogs.

Dosage for each species, route(s) of administration and method of administration
Dosing regimen:
The minimum recommended dose is: 10 mg/kg body weight (b.w.) imidacloprid and 50 mg/kg body weight (b.w.) permethrin, equivalent to
0.1ml/kg b.w. Advantix spot-on solution for dogs.

Dog's weight (kg) Pipette size to be used Volume (ml) Imidacloprid (mg/kg b.w.) Permethrin (mg/kg b.w.)

>25 kg - 40 kg Advantix spot-on solution for dogs over 25 kg 4.0 ml 10 - 16 50 - 80
> 40 kg the appropriate combination of pipettes should be used

Dog's weight (kg) Pipette size to be used Volume (ml) Imidacloprid(mg/kg b.w.) Permethrin (mg/kg b.w.)
<=4 kg Advantix spot-on solution for dogs up to 4 kg 0.4 ml minimum 10 minimum 50
>4 kg - 10 kg Advantix spot-on solution for dogs from 4 kg to 10 kg 1.0 ml 10 - 25 50 - 125
>10 kg - 25 kg Advantix spot-on solution for dogs from 10 kg to 25 kg 2.5 ml 10 - 25 50 - 125
>25 kg - 40 kg Advantix spot-on solution for dogs over 25 kg 4.0 ml 10 - 16 50 - 80
> 40 kg the appropriate combination of pipettes should be used

To reduce re-infestations with new fleas, it is recommended that all dogs in a family (household) be treated. Other pets in
the same family or household must be treated with appropriate products. For fleas originating from the animal's environment,
the additional use of an appropriate product for the treatment against adult fleas and their developmental stages is recommended. The product is active even if the animal is wet. However, prolonged exposure to water should be avoided. In case of prolonged exposure
to water, the product's efficacy decreases. Even in this case, it should not be treated more frequently than once a week. If it is
necessary to wash the animal with shampoo, it is advisable to apply Advantix spot-on solution for dogs two weeks later
to ensure the product's efficacy.

Method of administration.
Remove a pipette from the package. Hold the pipette upright, twist the cap and remove it. Turn the cap upside down and use it to
unseal the pipette (by twisting and pressing on the seal, as shown in the photo).
For dogs weighing 10 kg or less:
With the dog standing, part the fur between the shoulder blades until the skin is visible. Apply the tip of the pipette directly to the skin and
empty the contents of the pipette by firmly squeezing it several times. Apply only to intact skin.
For dogs weighing more than 10 kg:
With the dog standing, the entire content of the Advantix spot-on solution for dogs pipette will be applied evenly in four places,
starting from between the shoulder blades and extending to the base of the tail. At each spot, part the fur until the skin is visible. Apply the tip of the pipette to the skin and
gently squeeze to release some of the solution onto the skin.

Recommendations for correct administration
For external use only.
Apply only to intact skin.
Do not apply a large amount of solution in one spot, as this may run off onto the dog's sides.

Withdrawal period
Not applicable.

Special precautions for storage
Keep out of the sight and reach of children.
Do not freeze.
After opening the aluminum pouch, store in a dry place and do not store above 30°C.
The abbreviation used for the expiry date on the label, pipette and pouch is EXP.

Special precautions for use in animals
The content of the pipette must not come into contact with the eyes or mouth of the treated dog.
Pay attention to the correct administration of the product as described in the Method of administration section. In particular, oral ingestion
by licking the application site or contact with other animals should be avoided.
Do not use in cats.
This product is highly toxic to cats and can cause death due to the physiological particularities of cats,
which are unable to metabolize certain compounds including permethrin. To prevent accidental exposure of
cats to this product, treated dogs should be kept separate from cats after treatment until the application site is dry.
Measures should be taken to ensure that cats do not lick the application site of dogs that have been treated with this product. Seek
immediate veterinary assistance if this occurs.
Consult your veterinarian before using this product in sick and debilitated animals.
As the product is dangerous for aquatic organisms, treated dogs must under no circumstances be allowed to enter any surface waters
for at least 48 hours after treatment.

Special precautions to be taken by the person administering the veterinary medicinal product to animals
Avoid contact with skin, eyes or mouth. Do not eat, drink or smoke during product application.
Wash hands thoroughly after product application.
If the product accidentally gets on the skin, immediately wash the area with soap and water.
People with known skin sensitivity may be particularly sensitive to this product.
If the product accidentally gets into the eyes, wash the eyes with plenty of water. If skin or eye symptoms persist, or the product is
accidentally swallowed, seek immediate medical advice and show the doctor the product leaflet.
Treated dogs should not be allowed to play, especially with children, until the application site is dry. To be safe, treat dogs in the
evening, for example. In this case, treated dogs are not allowed to sleep with their owners, especially if they are children.

Special precautions for the disposal of unused product or waste, if applicable
After use, put the cap back on the pipette. Any unused veterinary medicinal product or waste derived from the use of such
products must be disposed of in accordance with local requirements.

Other information
Advantix spot-on solution for dogs is a topical ectoparasiticide containing imidacloprid and permethrin.
This combination acts as an insecticide, acaricide and repellent.

Imidacloprid is an ectoparasiticide belonging to the chloronicotinyl group of compounds. Chemically, it can be classified
as a chloronicotinyl nitroguanidine. Imidacloprid is effective against adult fleas and their larval stages. In addition to its
efficacy against adult fleas, the larvicidal efficacy of the substance for areas in the animal's habitat has also been demonstrated.
The product provides repellent (anti-feeding) action against ticks, sandflies and mosquitoes, thereby preventing
parasite blood feeding and reducing the risk of transmission of vector-borne diseases (Canine Vector-Borne Disease or
CVBD, such as borreliosis, rickettsiosis, ehrlichiosis, leishmaniasis).
It can be used during pregnancy and lactation.
The solvent in Advantix spot-on solution for dogs may stain certain materials such as leather, fabrics, plastic and finished surfaces. Allow
the application site to dry before contact with such materials.

Packaging:
Pipettes of 0.4 ml, 1.0 ml, 2.5 ml, 4.0 ml
Blister containing 1, 2, 3, 4 or 6 individual pipettes.
Not all package sizes may be marketed.
For any information regarding this veterinary medicinal product, please contact the local representative of the marketing authorisation holder.

Marketing Authorisation Holder
Bayer Animal Health GmbH, D-51368 Leverkusen, Germany

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